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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
penicillin-binding protein 2
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "penicillin-binding protein 2" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: WCK-5107
Research Areas:
Zidebactam (WCK-5107) is a potent β-lactamase inhibitor . Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL .
1
1 Cited Publications
Synonyms: T-91825; PPI-0903M
Target:
Research Areas:
Ceftaroline (T-91825) is a cephalosporin compound and the active form of Ceftaroline fosamil (HY-14737). Ceftaroline exhibits activity against Gram-positive bacteria, Gram-negative bacteria, and some anaerobic bacteria. Ceftaroline binds to penicillin-binding proteins 2 and 2A, thereby inhibiting the synthesis of bacterial peptidoglycan and cell wall, and acts as a bactericide, synergist, and resistance inhibitor. Ceftaroline can be used in research related to complicated skin and soft tissue infections, community-acquired pneumonia, Enterococcus faecalis infective endocarditis, and bacterial infections .
1
1 Cited Publications
Cat. No.: HY-105049A
Research Areas:
Ceftaroline hydrochloride is a cephalosporin compound and the active form of Ceftaroline fosamil (HY-14737). Ceftaroline hydrochloride exhibits activity against Gram-positive bacteria, Gram-negative bacteria, and some anaerobic bacteria. Ceftaroline hydrochloride binds to penicillin-binding proteins 2 and 2A, thereby inhibiting the synthesis of bacterial peptidoglycan and cell wall, and acts as a bactericide, synergist, and resistance inhibitor. Ceftaroline hydrochloride can be used in research related to complicated skin and soft tissue infections, community-acquired pneumonia, Enterococcus faecalis infective endocarditis, and bacterial infections .
Cat. No.: HY-120859A
CAS No.: 1706777-46-9
Synonyms: WCK-5107 sodium salt
Research Areas:
Zidebactam sodium salt (WCK-5107 sodium salt) is a potent β-lactamase inhibitor . Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL .
Cat. No.: HY-120859R
CAS No.: 1436861-97-0
Synonyms: WCK-5107 (Standard)
Research Areas:
Zidebactam (Standard) is the analytical standard of Zidebactam. This product is intended for research and analytical applications. Zidebactam (WCK-5107) is a potent β-lactamase inhibitor . Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL .
Cat. No.: HY-120366
CAS No.: 1452460-79-5
Research Areas:
WCK-5153 is a Penicillin-Binding Protein 2 (PBP2) inhibitor with an IC50 of 0.14 μg/ml (for P. aeruginosa PBP2) and acts as a β-lactam enhancer against Pseudomonas aeruginosa. WCK-5153 can be used in studies of multidrug-resistant (MDR) pathogens .
Cat. No.: HY-139699
CAS No.: 2842084-52-8
Synonyms: LCB18-055
Research Areas:
GT-055 (LCB18-055) is a broad-spectrum β-lactamase inhibitor and penicillin-binding protein 2 (PBP2) inhibitor. GT-055 inactivates β-lactamase, protects GT-1 from hydrolysis, and binds tightly to PBP2, thereby inhibiting cell wall biosynthesis. GT-055 can be used for research on bacterial infections .
Cat. No.: HY-187939
CAS No.: 2092930-66-8
Synonyms: LCB18-055 free base
Research Areas:
GT-055 free base (LCB18-055 free base) is a broad-spectrum β-lactamase inhibitor and penicillin-binding protein 2 (PBP2) inhibitor. GT-055 free base inactivates β-lactamase, protects GT-1 from hydrolysis, and binds tightly to PBP2, thereby inhibiting cell wall biosynthesis. GT-055 free base can be used for research on bacterial infections .
Cat. No.: HY-105049B
CAS No.: 614758-10-0
Synonyms: T-91825 chloride hydrochloride; PPI-0903M chloride hydrochloride
Research Areas:
Ceftaroline chloride hydrochloride (T-91825 chloride hydrochloride) is a cephalosporin compound and the active form of Ceftaroline fosamil (HY-14737). Ceftaroline chloride hydrochloride exhibits activity against Gram-positive bacteria, Gram-negative bacteria, and some anaerobic bacteria. Ceftaroline chloride hydrochloride binds to penicillin-binding proteins 2 and 2A, thereby inhibiting the synthesis of bacterial peptidoglycan and cell wall, and acts as a bactericide, synergist, and resistance inhibitor. Ceftaroline chloride hydrochloride can be used in research related to complicated skin and soft tissue infections, community-acquired pneumonia, Enterococcus faecalis infective endocarditis, and bacterial infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
