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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
193 Results for "
phosphatidylinositol
" in MedChemExpress (MCE) Product Catalog:
Products (193)
193 Results for "phosphatidylinositol" in MCE Product Catalog:
1221
1221 Publications Verification
Target:
Research Areas:
LY294002 hydrochloride is a potent and broad-spectrum PI3K inhibitor, with IC50 values of 0.5, 0.57, and 0.97 μM for P110α, P110δ and P110β, respectively. LY294002 hydrochloride also inhibits CK2 with an IC50 of 98 nM. LY294002 hydrochloride can be used for pancreatic cancer research .
11
11 Cited Publications
Cat. No.: HY-P1902
CAS No.: 115722-23-1
Target:
11
11 Cited Publications
Cat. No.: HY-P1902A
CAS No.: 2918768-05-3
Target:
9
9 Cited Publications
PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.47 μM. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis .
8
8 Cited Publications
Synonyms: C48/80 trihydrochloride
Target:
Research Areas:
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets .
8
8 Cited Publications
Cat. No.: HY-P80846
Synonyms: PIK3R1; GRB1; phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s
7
7 Cited Publications
Cat. No.: HY-P81211
Synonyms: PI3-kinase p110 subunit beta; p-PI3Kβ(Ser1070); PI 3-kinase C2β; p110 BETA; p110Beta; phosphatidylinositol 3 kinase catalytic beta polypeptide; phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit beta; phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit beta isoform; phosphatidylinositol-4; Phosphoinositide 3 kinase catalytic beta polypeptide; PI3 kinase p110 subunit beta; PI3-kinase subunit beta; PI3K; PI3K beta; PI3K-beta; PI3Kbeta; PI3KCB; PIK3C1; Pik3cb; PK3CB_HUMAN; PtdIns 3 kinase p110; PtdIns-3-kinase subunit beta; PtdIns-3-kinase subunit p110-beta; 5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; 5-bisphosphate 3-kinase catalytic subunit beta isoform.
6
6 Cited Publications
Cat. No.: HY-U00426
CAS No.: 1436383-95-7
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Research Areas:
BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC50 of 5.7 nM.
4
4 Cited Publications
T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC50 of 60 nM.
4
Category:
Alkaloids Rutaceae Quinoline Alkaloids Plants Skimmia reevesiana Fort. Disease Research Fields Inflammation/Immunology
Target:
4
4 Cited Publications
Cat. No.: HY-P80867
Synonyms: PIK3R1; GRB1; phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s
2
2 Cited Publications
GSK-A1 is a selective type III phosphatidylinositol 4-kinase PI4KA (PI4KIIIα) inhibitor with a pIC50 of 8.5-9.8. GSK-A1 inhibits PtdIns(4,5)P2 resynthesis with an IC50 of about 3 nM. GSK-A1 potently decreases the levels of PtdIns(4)P with a negligible effect on PtdIns(4,5)P2. GSK-A1 has the potential for anti-hepatitis C virus (HCV) research .
2
2 Cited Publications
Target:
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
1-Oleoyl-2-acetyl-sn-glycerol is a cell-permeable analog of diacylglycerol (DAG) and can activate Protein kinase C (PKC). 1-Oleoyl-2-acetyl-sn-glycerol can activate the TRPC channels-mediated specific Ca 2+ influx. 1-Oleoyl-2-acetyl-sn-glycerol can stimulate superoxide-generation from human neutrophils. 1-Oleoyl-2-acetyl-sn-glycerol stimulates the formation of phosphatidylinositol 4-phosphate in intact human platelets. 1-Oleoyl-2-acetyl-sn-glycerol can stimulate ascites tumor cell proliferation .
1
1 Cited Publications
Cat. No.: HY-W020658
CAS No.: 97281-52-2
Target:
1
1 Cited Publications
Cat. No.: HY-P1116
CAS No.: 794466-43-6
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P1116A
Target:
Research Areas:
1
1 Cited Publications
Synonyms: I-OMe-AG 538
Target:
Research Areas:
I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells.?I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC50?of 1 μM .
1
1 Cited Publications
Cat. No.: HY-P703580
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PIK3CA; phosphatidylinositol-4,5-Bisphosphate 3-Kinase; phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha; PI3-Kinase P110 Subunit Alpha; phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Isoform; PtdIns-3-Kinase
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Synonyms: Inositol 1,4,5-trisphosphate tripotassium; Ins(1,4,5)-P3 tripotassium
Target:
Research Areas:
D-myo-Inositol 1,4,5-trisphosphate tripotassium, a second messenger, elicits Ca 2+ mobilization. D-myo-Inositol 1,4,5-trisphosphate tripotassium inhibits the binding of phosphoinositide-specific phospholipase C-delta 1 (PLC-delta 1) to bilayer membranes composed of phosphatidylcholine (PC) and phosphatidylinositol 4,5-bisphosphate (PIP2) .
1
1 Cited Publications
Cat. No.: HY-163001
CAS No.: 2408008-21-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
