20 Results for "

phthalide

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "phthalide" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N0743
CAS No.: 63038-10-8
Senkyunolide A is a phthalide, anti-tumor cell proliferation agent with anticancer activity. Senkyunolide A protects neurons from corticosterone (HY-B1618)-induced apoptosis by decreasing protein phosphatase PP2A and α-synuclein phosphorylation and protein level. Senkyunolide A also inhibits osteoarthritis through the NLRP3 signaling pathway and suppresses the expression of CD137, a diagnostic biomarker for atherosclerosis .
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Cat. No.: HY-N0401
CAS No.: 4431-01-0
Ligustilide is is a bioactive phthalide derivative isolated from Angelica sinensis and Chuanxiong. Ligustilide exhibits neuroprotective, anti-cancer, anti-inflammatory, and vasodilator effects .
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Cat. No.: HY-W015820
CAS No.: 87-41-2
Phthalide is a chemical scaffold. Phthalide derivatives act as potent blood-brain barrier modulators. Phthalide exhibits significant anti-inflammatory activity. Some phthalide derivatives possess anti-inflammatory activity. The phthalide derivative Senkyunolide I shows analgesic effects and ameliorates cerebral edema and cerebral infarction volume in rats with focal cerebral ischemia-reperfusion injury. Phthalide can be used in research related to glioma, rheumatoid arthritis, malaria, bacterial infection, fungal infection and ischemic stroke .
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Cat. No.: HY-N8558A
CAS No.: 94530-86-6
Senkyunolide J, a phthalide, can be isolated from rhizome of Ligusticum Chuanxiong .
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Cat. No.: HY-N8558
CAS No.: 140694-58-2
Target:  

Drug Derivative

Research Areas:  

Others

Senkyunolide N, a phthalide, can be isolated from rhizome of Ligusticum Chuanxiong .
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Cat. No.: HY-W782599
CAS No.: 93236-67-0
Senkyunolide B is a phthalide found in Angelica sinensis. Senkyunolide B has broad antifungal activities. Senkyunolide B affects the spore germination and hyphae growth of Aspergillus fumigatus via down-regulating phosphatidylinositol-PKC-calcineurin axis and the expression of ENG genes .
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Cat. No.: HY-B0647A
CAS No.: 3413-15-8
Synonyms: (-)-3-n-Butylphthalide; (3S)-Butylphthalide
(3S)-Butylphthalide is a phthalide and can be isolated from A. graveolens. (3S)-Butylphthalide has antiplatelet and neuroprotective activities .
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Cat. No.: HY-W015820R
CAS No.: 87-41-2
Phthalide (Standard) is an analytical standard of Phthalide. This product is intended for research and analytical applications. Phthalide is a chemical scaffold. Phthalide can be used to synthesize a variety of phthalate derivatives, including anti-inflammatory agents, antimicrobial agents, antioxidants and blood-tumor barrier regulators .
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Cat. No.: HY-W002463
CAS No.: 63503-60-6
3-Chlorophenylboronic acid is employed as a reactant involved in 1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides, Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene, cross-coupling reactions with diazoesters3 or potassium cyanate. 3-Chlorophenylboronic acid is involved in the synthesis of biarylketones and phthalides and synthesis of inhibitors including PDE4 inhibitors among others. 3-Chlorophenyl boronic acid can affect cell migration. 3-Chlorophenyl boronic acid can be used to study wound healing .
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Cat. No.: HY-W140555
CAS No.: 3465-69-8
Research Areas:  

Infection

5,7-Dimethoxyphthalide, a dimethoxy derivative of phthalide, can undergo nucleophilic substitution reactions with functionalized long-chain alkyl iodides. 5,7-Dimethoxyphthalide acts as a synthetic building block to prepare anti-Helicobacter pylori products including CJ molecule and sporotricale methyl ether. 5,7-Dimethoxyphthalide can be utilized for relevant researches on Helicobacter pylori infection and structure-activity relationship (SAR) .
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Cat. No.: HY-N1350
CAS No.: 89354-45-0
Riligustilide (compound 2) is a kind of phthalide dimer. Riligustilide can be isolated from the radix of Angelica sinensis .
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Cat. No.: HY-164643
CAS No.: 1373311-69-3
Target:  

Antibiotic Fungal

Research Areas:  

Infection

Antifungal agent 113 (compound 9a) is a potent antifungal and antibacterial agent. Antifungal agent 113 shows good antibacterial activity against S. aureus and methicillin-resistant S. aureus .
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Cat. No.: HY-N10280
CAS No.: 2701570-79-6
Asperglaucin A represents an unusual phthalide-like derivative. Asperglaucin A exhibits potent antibacterial activities against two plant pathogens Pseudomonas syringae pv actinidae (Psa) and Bacillus cereus, with an MIC value of 6.25 μM .
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Cat. No.: HY-N13769
CAS No.: 172723-28-3
Senkyunolide S is a phthalide that can be found in the rhizome of Ligusticum chuanxiong .
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Cat. No.: HY-183212
CAS No.: 166733-97-7
Target:  

Others

Research Areas:  

Others

(±)-Sedanenolide is a phthalide compound that can be isolated from the seeds of Apium graveolens L. .
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Cat. No.: HY-165368
CAS No.: 519-67-5
Target:  

Bacterial

Atromentin, a phthalide derivative that can be isolated from the wood fungus Hypoxylon fendleri BCC32408, is a selective enoyl-ACP reductase FabK inhibitor with an IC50 of 0.24 μM. Atromentin exhibits selectivity over FabI. Atromentin can be used for antimicrobial research .
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Cat. No.: HY-11033
CAS No.: 1007399-87-2
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

DNP-60502 is a phthalide derivative. DNP-60502 exhibits potent glucose production inhibitory activity by targeting key regulatory enzymes in hepatic glucose metabolism. DNP-60502 can be used for the study of type 2 diabetes .
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Cat. No.: HY-N17975
CAS No.: 210036-10-5
(Z)-6,7-Epoxyligustilide (Compound 8) is a Phthalide (HY-W015820) derivative found in the rhizomes of Ligusticum wallichii .
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Cat. No.: HY-135631
CAS No.: 172549-37-0
Senkyunolide R is a phthalide compound that can be naturally extracted from the dried rhizomes of Ligusticum chuanxiong HORT .
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Cat. No.: HY-N18209
CAS No.: 74459-23-7
4-Hydroxy-3-butylphthalide is a Phthalide (HY-W015820) derivative found in the rhizome of Ligusticum ChuanXiong Hort. 4-Hydroxy-3-butylphthalide binds core targets linked to lung cancer brain metastasis, such as BDNF, FOS, and MAPK14. 4-Hydroxy-3-butylphthalide can be used for the research of lung cancer brain metastasis .
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