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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
propionic acidemia
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "propionic acidemia" in MCE Product Catalog:
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-159509
CAS No.: 2361124-03-8
Synonyms: Claziprotamide; BBP-671
Target:
Research Areas:
Claziprotamidum (Claziprotamide; BBP-671) is a panthothenate kinase (PANK) activator with oral activity and blood-brain barrier permeability. Claziprotamidum binds to and activates all PANK isoforms, with the highest affinity for PANK3 (KD = 97 pM; IC50 = 1.39 nM). Claziprotamidum increases the intracellular biosynthesis of Coenzyme A (HY-128851) and restores mitochondrial function. Claziprotamidum can be used in the research of pantothenate kinase-associated neurodegeneration and propionic acidemia .
Synonyms: Methylcitric acid trisodium
Target:
Cat. No.: HY-164909
CAS No.: 2170608-85-0
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Research Areas:
PZ-3022 is an orally active allosteric agonist of pantothenate kinase (PanK) with an EC50 of 5.3 nM against PanK3. PZ-3022 antagonizes the inhibitory effect of C3-CoA. PZ-3022 increases CoA levels in cells and the liver, upregulates CoASH and C2-CoA, downregulates C3-CoA, and restores impaired TCA cycle and mitochondrial function. PZ-3022 can be used for the research of propionic acidemia and metabolic CoA deficiency .
Category:
Natural Products Animals Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
Synonyms: Methylcitric acid-d3
Cat. No.: HY-P1162
CAS No.: 73168-24-8
Synonyms: SKF 100273
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Research Areas:
Cat. No.: HY-P2595
CAS No.: 111372-60-2
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
