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Results for "

secreted protein

" in MedChemExpress (MCE) Product Catalog:

By Targets:	sFRP-1 (4) AMPK (1) Antibiotic (3) Apoptosis (5) Autophagy (2) Bacterial (2) Biochemical Assay Reagents (3) COX (1) Endogenous Metabolite (2) Epigenetic Reader Domain (1) Ferroptosis (1) GSK-3 (1) HBV (1) HSP (1) HSV (2) JAK (1) Leukotriene Receptor (1) Lipase (2) Lipoxygenase (1) Mitophagy (2) MMP (1) mRNA (6) p38 MAPK (1) PROTACs (1) Protease Activated Receptor (PAR) (1) Reference Standards (2) STAT (1) TGF-β Receptor (1) Thrombin (1) TNF Receptor (1) Vasopressin Receptor (1) VEGFR (1) Wnt (4) β-catenin (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (4) Infection (6) Inflammation/Immunology (6) Metabolic Disease (3) Neurological Disease (4)
Oligonucleotides:	Interferon & Receptors (1) Chemokine & Receptors (1) Aptamers (1) mRNA (6)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Osteopontin sFRP-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16592

Brefeldin A 150+ Cited Publications BFA; Cyanein; Decumbin	Autophagy Mitophagy HSV Antibiotic Bacterial	Infection Cancer
Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus . Brefeldin A is also an autophagy and mitophagy inhibitor . Brefeldin A inhibits HSV-1 and has anti-cancer activity .

HY-10858

WAY 316606 4 Publications Verification	sFRP-1 Wnt	Cancer
WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC₅₀ of 0.5 μM .

HY-P10735

GIP (mouse) Gastric inhibitory polypeptide(mouse); GIP(1-42) (mouse)	Lipase Apoptosis	Metabolic Disease
GIP (Gastric inhibitory polypeptide) (mouse) is a gastrointestinal hormone that is secreted by the intestinal K cells, and also expressed in and secreted from pancreatic islets. GIP (mouse) promotes insulin secretion from pancreatic β cells via the G-protein-coupled GIP receptor (GIPR). GIP (mouse) promotes pancreatic β cell proliferation and inhibits apoptosis. GIP (mouse) also exerts direct lipogenic effects on adipose tissue .

HY-NP006

Protein A 1 Publications Verification SPA	Endogenous Metabolite Apoptosis	Inflammation/Immunology
Protein A (SPA) is an immunoglobulin (Ig)-binding protein that exists on the bacterial surface and can be freely secreted into the extracellular environment. Protein A blocks opsonophagocytosis and induces B cell apoptosis in vitro by binding to the Fc region of antibodies and the Fab region of B cell receptors. Protein A can form toxic immune complexes with IgG, thereby inducing leukocyte necrosis. Protein A contributes to the virulence expression of Staphylococcus aureus. Protein A triggers allergic reactions in IgG-pretreated mouse models. Protein A can be used in studies related to immune system diseases .

HY-D0166A

Neutral Red (IND)	Biochemical Assay Reagents	Others
Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, etc., and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant. Although the compound has no direct medical application, it has important application value in the fields of biology, chemistry and industry.

HY-112331

SJ000291942 3 Publications Verification	TGF-β Receptor	Cancer
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway. BMPs are members of the transforming growth factor beta (TGFβ) family of secreted signaling molecules.

HY-114164G

Murine Thrombin	Thrombin Protease Activated Receptor (PAR) MMP VEGFR Epigenetic Reader Domain	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Murine Thrombin is a murine serine protease that plays a central role in blood coagulation. Murine Thrombin stimulates macrophages to polarize into a unique phenotype characterized by anti-inflammatory and pro-repair properties. Murine Thrombin activates PAR1, induces the production of MCP-1, MMP3 and VEGF in mouse intervertebral discs, and causes degradation of the cartilage matrix and destruction of intervertebral disc structure. Murine Thrombin activity increases significantly in paraoxon-induced status epilepticus .

HY-168894

CT-1	Ferroptosis JAK STAT p38 MAPK AMPK GSK-3 Apoptosis HSP TNF Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
CT-1 is a secreted protein belonging to the IL-6 cytokine family. Overexpression of CT-1 enhances cell proliferation, migration and angiogenesis via the ADMA/DDAH pathway. CT-1 inhibits the growth of triple-negative breast cancer cells by simultaneously inducing Ferroptosis in N2-type tumor-associated neutrophils and cancer cells. CT-1 activates the Jak/STAT-3, p42/p44 MAPK and AMPK pathways, and inhibits GSK-3β activity through phosphorylation to induce cardiomyocyte hypertrophy. CT-1 enhances the viability of cardiomyocytes and neurons, reduces cell Apoptosis, induces the expression of heat shock proteins (HSP) and BNP, and inhibits TNF levels. CT-1 exerts anti-tumor activity in mouse models of triple-negative breast cancer. CT-1 improves cognitive impairment in mice. CT-1 is applicable to the research of ischemic heart disease, triple-negative breast cancer, myocardial hypertrophy, Parkinson's disease, hypertensive heart disease, myocardial infarction, acute Chagas cardiomyopathy, high-fat diet-induced cognitive impairment and diabetes-related cognitive impairment .

HY-W089800

trans-2-Nonenal trans-2-Nonen-1-al	COX Lipoxygenase Apoptosis	Cardiovascular Disease Inflammation/Immunology
trans-2-Nonenal (trans-2-Nonen-1-al) is an endogenous peroxidation product of polyunsaturated fatty acids, acting as an inhibitor of COX and 12-LOX, as well as an inducer of apoptosis. trans-2-Nonenal is also a malodorous compound secreted by the human body, and its content gradually increases with aging. trans-2-Nonenal inhibits the activities of multiple enzymes such as platelet membrane-bound PTPase, preferentially covalently modifies proteins at lysine residues to form immunogenic adducts, and regulates platelet Arachidonic acid (HY-109590) metabolism. trans-2-Nonenal also exhibits significant cytotoxicity, reduces the viability of keratinocytes, promotes their apoptosis, and effectively decreases the thickness of epidermal models and the number of proliferating cells. trans-2-Nonenal is commonly used in studies of thrombotic, atherosclerotic diseases, renal adenocarcinoma, etc. .

HY-10860

WAY-362692	sFRP-1 Wnt β-catenin	Metabolic Disease
WAY-362692 is a **secreted frizzled-related protein (sFRP-1) inhibitor (IC₅₀ of 0.02 μM), targeting the netrin domain of sFRP-1. WAY-362692 can competitively inhibit the interaction between sFRP-1 and Wnt** proteins, and activate the Wnt/β-catenin signaling pathway (EC₅₀ = 0.03 μM). WAY-362692 can activate osteoblasts and promote bone remodeling. WAY-362692 can be used for the research of metabolic disease, such as osteoporosis .

HY-10858A

WAY 316606 hydrochloride 4 Publications Verification	sFRP-1 Wnt	Cancer
WAY 316606 hydrochloride is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC₅₀ of 0.5 μM .

HY-16592R

Brefeldin A (Standard) BFA (Standard); Cyanein (Standard); Decumbin (Standard)	Reference Standards Autophagy Mitophagy HSV Antibiotic Bacterial	Infection Cancer
Brefeldin A (Standard) (BFA (Standard)) is the analytical standard of Rutin. This product is intended for research and analytical applications. Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A inhibits HSV-1 and has anti-cancer activity.

HY-N7698

Tetra-N-acetylchitotetraose	Biochemical Assay Reagents	Others
Tetra-N-acetylchitotetraose is a linear chitosan oligosaccharide. Tetra-N-acetylchitotetraose is a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia. Tetra-N-acetylchitotetraose is also a substrate for the Rhizobium leguminosarum nodulation protein NodB, a CO deacetylase .

HY-P0049A

Argipressin diacetate Arg8-vasopressin diacetate; AVP diacetate; ADH	Apoptosis Vasopressin Receptor	Neurological Disease Cancer
Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary. Argipressin (diacetate) (AVP (diacetate)) can regulate the biological effects of fluid balance, osmolality and cardiovascular through three separate G-protein coupled receptors (GPCRs), namely Avpr1a (V1a), Avpr1b (V1b) and Avpr2 (V2). Argipressin (diacetate) (AVP (diacetate)) also have potentially important effects on centrally regulated metabolic processes .

HY-127113

Q8	Leukotriene Receptor	Cardiovascular Disease
Q8, an effective antiangiogenic drug, is a CysLt₁ antagonist (IC₅₀ of 4.9 μM). Q8 is sufficient to reduce cellular levels of NF-κB and calpain-2 and secreted levels of the proangiogenic proteins intercellular adhesion molecule-1, vascular cell adhesion protein-1, and VEGF .

HY-174662

Human IFNG mRNA	mRNA	Inflammation/Immunology
Human IFNG mRNA encodes the human interferon gamma (IFNG) protein, a member of the type II interferon class. IFNG is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections.

HY-118481

H-Pro-Glu-OH	Lipase	Infection
H-Pro-Glu-OH is a protein secreted by pathogenic mycobacteria through the Type VII secretion system. H-Pro-Glu-OH targets LipY lipases to the cell Surface via the ESX-5 Pathway .

HY-174772

Human CCL1 mRNA	mRNA	Inflammation/Immunology
Human CCL1 mRNA encodes the human C-C motif chemokine ligand 1 (CCL1) protein, a member of the CC subfamily. CCL1 is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils.

HY-174533

Human TGFB2 mRNA	mRNA	Cancer
Human TGFB2 mRNA encodes the human transforming growth factor beta 2 (TGFB2) protein, a secreted ligand of the TGF-beta superfamily. TGFB2 has suppressive effects on interleukin-2 dependent T-cell growth.

HY-174700

Human FGF21 mRNA	mRNA	Cancer
Human FGF21 mRNA encodes the human fibroblast growth factor 21 (FGF21) protein, a member of the fibroblast growth factor (FGF) family. FGF21 is a secreted endocrine factor that functions as a major metabolic regulator. It stimulates the uptake of glucose in adipose tissue.

HY-145741

MptpB-IN-1	Antibiotic	Infection
MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden .

HY-174534

Human TGFB1 mRNA	mRNA	Cancer
Human TGFB1 mRNA encodes the human transforming growth factor beta 1 (TGFB1) protein, a secreted ligand of the TGF-beta superfamily. TGFB1 can regulate cell proliferation, differentiation and growth, and also play a role in modulating expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha.

HY-W127485

cis-9,10-Methyleneoctadecanoic Acid	Biochemical Assay Reagents	Others
cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and in the digestive glands of P. globosa. It is a component of the cell membrane of Staphylococcus aureus, and levels were reduced after treatment with carvacrol. cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells. It also activates protein kinase C (PKC) in a calcium-dependent manner.

HY-P11092

TLQP-62 (mouse,rat)	Endogenous Metabolite	Neurological Disease
TLQP-62 (mouse,rat) is a secreted C-terminal peptide that can be derived from protein VGF. TLQP-62 activates the BDNF-TrkB signaling pathway, inducing acute, transient phosphorylation of TrkB receptor and downstream CREB (Ser133) phosphorylation. TLQP-62 demonstrates excellent efficacy in promoting long-term fear memory formationin wild-type mice and reversing memory impairment in VGF heterozygous knock-out mice. TLQP-62 can be used for the study of memory-related neurological disorders (e.g., Alzheimer’s disease, frontotemporal dementia) .

HY-174856

PROTAC HBeAg degrader-1	PROTACs HBV	Infection
PROTAC HBeAg degrader-1 is a PROTAC targeting degradation agent for HBeAg. PROTAC HBeAg degrader-1 recruits the VHL E3 ligase but degrades HBV protein HBeAg through VHL-independent mechanism. PROTAC HBeAg degrader-1 decreases levels of secreted and intracellular HBeAg. PROTAC HBeAg degrader-1 can be used for the research of hepatitis B virus (HBV) . (Structure Note: Pink: HBeAg ligand (HY-174857); Blue: VHL Ligand (HY-125845); Black: linker; E3-linker (HY-135045))

HY-10858R

WAY 316606 (Standard)	Reference Standards sFRP-1 Wnt	Cancer
WAY 316606 (Standard) is the analytical standard of WAY 316606 (HY-10858). This product is intended for research and analytical applications. WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC₅₀ of 0.5 μM .

HY-174532

Human TGFB3 mRNA	mRNA	Cancer
Human TGFB3 mRNA encodes the human transforming growth factor beta 3 (TGFB3) protein, a secreted ligand of the TGF-beta superfamily. TGFB3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing.

Cat. No.	Product Name

HY-L072

Exosomes Compound Library	53 compounds
Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining. The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 53 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

Exosomes Compound Library

53 compounds

Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining.

The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 53 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

HY-L132

Chemokine Compound Library	239 compounds
Chemokines, or chemotactic cytokines, are small cytokines or signaling proteins secreted by cells. They are a component of intercellular communication, controlling the directional movement of immune cells especially leukocytes, as well as other cell types, for instance, endothelial and epithelial cells, which are essential to maintain human health and the function of the immune system. The biological effects of chemokines are achieved by binding to chemokine receptors, which are G protein-coupled receptors found on the surface of leukocytes. Some chemokine receptors are involved in directing tumor metastasis and over-expression by certain tumors. So inhibiting the interaction between chemokine and chemokine receptors on the surface of tumor cells may be a new possible therapeutic approach. Some chemokine receptors are coreceptors for HIV entry, and related inhibitors have been approved by the FDA to treat patients with HIV. Obviously, chemokines and chemokine receptors have become new targets for studying cancer, HIV, inflammation, and other diseases. MCE supplies a unique collection of 239 chemokine or chemokine receptor inhibitors and activators, all of which have the identified inhibitory or activated effect on chemokine or chemokine receptors. MCE Chemokine Library is a useful tool for drug research related to cancer, AIDS, and wound therapy.

Chemokine Compound Library

239 compounds

Chemokines, or chemotactic cytokines, are small cytokines or signaling proteins secreted by cells. They are a component of intercellular communication, controlling the directional movement of immune cells especially leukocytes, as well as other cell types, for instance, endothelial and epithelial cells, which are essential to maintain human health and the function of the immune system.

The biological effects of chemokines are achieved by binding to chemokine receptors, which are G protein-coupled receptors found on the surface of leukocytes. Some chemokine receptors are involved in directing tumor metastasis and over-expression by certain tumors. So inhibiting the interaction between chemokine and chemokine receptors on the surface of tumor cells may be a new possible therapeutic approach. Some chemokine receptors are coreceptors for HIV entry, and related inhibitors have been approved by the FDA to treat patients with HIV. Obviously, chemokines and chemokine receptors have become new targets for studying cancer, HIV, inflammation, and other diseases.

MCE supplies a unique collection of 239 chemokine or chemokine receptor inhibitors and activators, all of which have the identified inhibitory or activated effect on chemokine or chemokine receptors. MCE Chemokine Library is a useful tool for drug research related to cancer, AIDS, and wound therapy.

HY-L168

Extracellular Vesicles (EVs) Compound Library	643 compounds
Extracellular vesicles (EVs) are small membrane binding structures that are released from cells into the surrounding environment and play a crucial role in mediating and regulating intercellular communication related to physiological and pathological processes. EVs are lipid membrane vesicles composed of proteins, lipids, and nucleic acids. EVs can be divided into several types based on their source, such as extracellular vesicles, microcapsules, and apoptotic vesicles. The size range of exosomes is 30-150nm, which are endocrine in multi vesicular endosomes (MVEs); microvesicles (50-1000nm) are secreted directly through extracellular interactions, thereby releasing plasma membrane vesicles. In contrast, apoptotic bodies are usually larger, ranging in size from 1 to 5 μ m. This is generated during programmed cell death. EV plays a crucial role in transmitting information between cells and influencing the behavior and function of receptor cells. MCE designs a unique collection of 643 small molecules related to extracellular vesicles (EVs). It is a good tool to be used for research on metabolize, cancer and other diseases.

Extracellular Vesicles (EVs) Compound Library

643 compounds

Extracellular vesicles (EVs) are small membrane binding structures that are released from cells into the surrounding environment and play a crucial role in mediating and regulating intercellular communication related to physiological and pathological processes. EVs are lipid membrane vesicles composed of proteins, lipids, and nucleic acids. EVs can be divided into several types based on their source, such as extracellular vesicles, microcapsules, and apoptotic vesicles. The size range of exosomes is 30-150nm, which are endocrine in multi vesicular endosomes (MVEs); microvesicles (50-1000nm) are secreted directly through extracellular interactions, thereby releasing plasma membrane vesicles. In contrast, apoptotic bodies are usually larger, ranging in size from 1 to 5 μ m. This is generated during programmed cell death. EV plays a crucial role in transmitting information between cells and influencing the behavior and function of receptor cells.

MCE designs a unique collection of 643 small molecules related to extracellular vesicles (EVs). It is a good tool to be used for research on metabolize, cancer and other diseases.

HY-L161

Cytokine Inhibitors Library	1,332 compounds
Cytokines are a kind of low molecular soluble proteins synthesized and secreted by immunogen, mitogen or other factors. They have functions of regulating innate and adaptive immune responses, promoting hematopoiesis, stimulating cell activation, proliferation and differentiation. The process of releasing a large number of cytokines is also called “Cytokine storm”, which can cause damage to many tissues and organs in the body. Cytokine is involved in the pathogenesis of many human diseases, including cancer, diabetes, chronic inflammatory diseases and so on. Cytokine inhibitors are a class of essential compounds that act by directly inhibiting the synthesis and release of cytokine or blocking the binding of cytokine to their receptors. Cytokine inhibitors are important compounds for the study of tumor and autoimmune diseases. MCE designs a unique collection of 1,332 cytokine inhibitors, mainly targeting the receptor interleukin (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), growth factor (GF) and chemokine, which is an effective tool for development and research of anti-cancer, anti-chronic inflammatory diseases and anti-autoimmune diseases compounds.

Cytokine Inhibitors Library

1,332 compounds

Cytokines are a kind of low molecular soluble proteins synthesized and secreted by immunogen, mitogen or other factors. They have functions of regulating innate and adaptive immune responses, promoting hematopoiesis, stimulating cell activation, proliferation and differentiation. The process of releasing a large number of cytokines is also called “Cytokine storm”, which can cause damage to many tissues and organs in the body. Cytokine is involved in the pathogenesis of many human diseases, including cancer, diabetes, chronic inflammatory diseases and so on. Cytokine inhibitors are a class of essential compounds that act by directly inhibiting the synthesis and release of cytokine or blocking the binding of cytokine to their receptors. Cytokine inhibitors are important compounds for the study of tumor and autoimmune diseases.

MCE designs a unique collection of 1,332 cytokine inhibitors, mainly targeting the receptor interleukin (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), growth factor (GF) and chemokine, which is an effective tool for development and research of anti-cancer, anti-chronic inflammatory diseases and anti-autoimmune diseases compounds.

Cat. No.	Product Name	Type

HY-D0166A

Neutral Red (IND)	Fluorescent Dyes
Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, etc., and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant. Although the compound has no direct medical application, it has important application value in the fields of biology, chemistry and industry.

Neutral Red (IND)

Fluorescent Dyes

Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, etc., and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant. Although the compound has no direct medical application, it has important application value in the fields of biology, chemistry and industry.

Cat. No.	Product Name	Type

HY-NP006

Protein A 1 Publications Verification SPA	Biochemical Assay Reagents
Protein A (SPA) is an immunoglobulin (Ig)-binding protein that exists on the bacterial surface and can be freely secreted into the extracellular environment. Protein A blocks opsonophagocytosis and induces B cell apoptosis in vitro by binding to the Fc region of antibodies and the Fab region of B cell receptors. Protein A can form toxic immune complexes with IgG, thereby inducing leukocyte necrosis. Protein A contributes to the virulence expression of Staphylococcus aureus. Protein A triggers allergic reactions in IgG-pretreated mouse models. Protein A can be used in studies related to immune system diseases .

Protein A

1 Publications Verification

SPA

Biochemical Assay Reagents

Protein A (SPA) is an immunoglobulin (Ig)-binding protein that exists on the bacterial surface and can be freely secreted into the extracellular environment. Protein A blocks opsonophagocytosis and induces B cell apoptosis in vitro by binding to the Fc region of antibodies and the Fab region of B cell receptors. Protein A can form toxic immune complexes with IgG, thereby inducing leukocyte necrosis. Protein A contributes to the virulence expression of Staphylococcus aureus. Protein A triggers allergic reactions in IgG-pretreated mouse models. Protein A can be used in studies related to immune system diseases .

HY-W089800

trans-2-Nonenal trans-2-Nonen-1-al	Biochemical Assay Reagents
trans-2-Nonenal (trans-2-Nonen-1-al) is an endogenous peroxidation product of polyunsaturated fatty acids, acting as an inhibitor of COX and 12-LOX, as well as an inducer of apoptosis. trans-2-Nonenal is also a malodorous compound secreted by the human body, and its content gradually increases with aging. trans-2-Nonenal inhibits the activities of multiple enzymes such as platelet membrane-bound PTPase, preferentially covalently modifies proteins at lysine residues to form immunogenic adducts, and regulates platelet Arachidonic acid (HY-109590) metabolism. trans-2-Nonenal also exhibits significant cytotoxicity, reduces the viability of keratinocytes, promotes their apoptosis, and effectively decreases the thickness of epidermal models and the number of proliferating cells. trans-2-Nonenal is commonly used in studies of thrombotic, atherosclerotic diseases, renal adenocarcinoma, etc. .

trans-2-Nonenal

trans-2-Nonen-1-al

Biochemical Assay Reagents

trans-2-Nonenal (trans-2-Nonen-1-al) is an endogenous peroxidation product of polyunsaturated fatty acids, acting as an inhibitor of COX and 12-LOX, as well as an inducer of apoptosis. trans-2-Nonenal is also a malodorous compound secreted by the human body, and its content gradually increases with aging. trans-2-Nonenal inhibits the activities of multiple enzymes such as platelet membrane-bound PTPase, preferentially covalently modifies proteins at lysine residues to form immunogenic adducts, and regulates platelet Arachidonic acid (HY-109590) metabolism. trans-2-Nonenal also exhibits significant cytotoxicity, reduces the viability of keratinocytes, promotes their apoptosis, and effectively decreases the thickness of epidermal models and the number of proliferating cells. trans-2-Nonenal is commonly used in studies of thrombotic, atherosclerotic diseases, renal adenocarcinoma, etc. .

HY-NP024

Snake poison protein	Biochemical Assay Reagents
Snake poison protein is a venom protein secreted by the salivary glands of venomous snakes .

HY-W127485

cis-9,10-Methyleneoctadecanoic Acid	Biochemical Assay Reagents
cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and in the digestive glands of P. globosa. It is a component of the cell membrane of Staphylococcus aureus, and levels were reduced after treatment with carvacrol. cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells. It also activates protein kinase C (PKC) in a calcium-dependent manner.

cis-9,10-Methyleneoctadecanoic Acid

Biochemical Assay Reagents

cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and in the digestive glands of P. globosa. It is a component of the cell membrane of Staphylococcus aureus, and levels were reduced after treatment with carvacrol. cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells. It also activates protein kinase C (PKC) in a calcium-dependent manner.

Cat. No.	Product Name	Target	Research Area

HY-P10735

GIP (mouse) Gastric inhibitory polypeptide(mouse); GIP(1-42) (mouse)	Lipase Apoptosis	Metabolic Disease
GIP (Gastric inhibitory polypeptide) (mouse) is a gastrointestinal hormone that is secreted by the intestinal K cells, and also expressed in and secreted from pancreatic islets. GIP (mouse) promotes insulin secretion from pancreatic β cells via the G-protein-coupled GIP receptor (GIPR). GIP (mouse) promotes pancreatic β cell proliferation and inhibits apoptosis. GIP (mouse) also exerts direct lipogenic effects on adipose tissue .

HY-P5364

B8R 20-27	Peptides	Others
B8R 20-27 is a biological active peptide. (This is amino acids 20 to 27 fragment of B8R, a vaccinia virus (VV) gene that encodes a secreted protein related to gamma interferon receptor. B8R binding to IFN-g neutralizes its antiviral activity.)

HY-P0049A

Argipressin diacetate Arg8-vasopressin diacetate; AVP diacetate; ADH	Apoptosis Vasopressin Receptor	Neurological Disease Cancer
Argipressin (diacetate) (AVP (diacetate), also known as antidiuretic hormone (ADH)) is a 9 amino acid neuropeptide secreted by the posterior pituitary. Argipressin (diacetate) (AVP (diacetate)) can regulate the biological effects of fluid balance, osmolality and cardiovascular through three separate G-protein coupled receptors (GPCRs), namely Avpr1a (V1a), Avpr1b (V1b) and Avpr2 (V2). Argipressin (diacetate) (AVP (diacetate)) also have potentially important effects on centrally regulated metabolic processes .

HY-P11092

TLQP-62 (mouse,rat)	Endogenous Metabolite	Neurological Disease
TLQP-62 (mouse,rat) is a secreted C-terminal peptide that can be derived from protein VGF. TLQP-62 activates the BDNF-TrkB signaling pathway, inducing acute, transient phosphorylation of TrkB receptor and downstream CREB (Ser133) phosphorylation. TLQP-62 demonstrates excellent efficacy in promoting long-term fear memory formationin wild-type mice and reversing memory impairment in VGF heterozygous knock-out mice. TLQP-62 can be used for the study of memory-related neurological disorders (e.g., Alzheimer’s disease, frontotemporal dementia) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-16592

Brefeldin A 150+ Cited Publications BFA; Cyanein; Decumbin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antiviral Disease Research Anticancer Disease Research Fields Source Classification	Autophagy Mitophagy HSV Antibiotic Bacterial
Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus . Brefeldin A is also an autophagy and mitophagy inhibitor . Brefeldin A inhibits HSV-1 and has anti-cancer activity .

HY-W089800

trans-2-Nonenal trans-2-Nonen-1-al	Source Classification	COX Lipoxygenase Apoptosis
trans-2-Nonenal (trans-2-Nonen-1-al) is an endogenous peroxidation product of polyunsaturated fatty acids, acting as an inhibitor of COX and 12-LOX, as well as an inducer of apoptosis. trans-2-Nonenal is also a malodorous compound secreted by the human body, and its content gradually increases with aging. trans-2-Nonenal inhibits the activities of multiple enzymes such as platelet membrane-bound PTPase, preferentially covalently modifies proteins at lysine residues to form immunogenic adducts, and regulates platelet Arachidonic acid (HY-109590) metabolism. trans-2-Nonenal also exhibits significant cytotoxicity, reduces the viability of keratinocytes, promotes their apoptosis, and effectively decreases the thickness of epidermal models and the number of proliferating cells. trans-2-Nonenal is commonly used in studies of thrombotic, atherosclerotic diseases, renal adenocarcinoma, etc. .

HY-16592R

Brefeldin A (Standard) BFA (Standard); Cyanein (Standard); Decumbin (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Antiviral Disease Research Anticancer Source Classification	Reference Standards Autophagy Mitophagy HSV Antibiotic Bacterial
Brefeldin A (Standard) (BFA (Standard)) is the analytical standard of Rutin. This product is intended for research and analytical applications. Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A inhibits HSV-1 and has anti-cancer activity.

Species:	Human (26) Rhesus Macaque (2) Rat (4) Mouse (9) Cynomolgus (3) Canine (1)
Tag:	His (36) Tag Free (3) Avi (4) Myc (2) Fc (8)
Source:	HEK293 (33) CHO (1) CHO (2) P. pastoris (2) E. coli (9)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704536

	RELM beta Protein, Human (His) Resistin-like beta; Cysteine-rich secreted protein A12-beta; Cysteine-rich secreted protein FIZZ2; RELMbeta; Retnlb; Fizz2	Human	E. coli

HY-P71259

	Resistin Protein, Human (His) 1 Publications Verification Resistin; Adipose tissue-specific secretory factor; Cysteine-rich secreted protein FIZZ3; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2; FIZZ3; HXCP1; RSTN; RETN	Human	E. coli
	Resistin, a hormone linking obesity to diabetes, may hinder insulin's glucose uptake stimulation in adipose cells, contributing to metabolic dysregulation. Additionally, it promotes myeloid cell chemotaxis and forms homodimers through disulfide linkages, interacting with DEFA1. Resistin's involvement in diverse cellular processes suggests its pivotal role in the complex interplay of metabolism, inflammation, and insulin responsiveness. Resistin Protein, Human (His) is the recombinant human-derived Resistin protein, expressed by E. coli , with C-6*His labeled tag.

HY-P71803

	*26 kDa secreted* antigen/TES-26 Protein, Canine (P.pastoris, His)** TES-2626kDa secreted antigen; Toxocara excretory-secretory antigen 26; TES-26	Canine	P. pastoris
	26 kDa secreted antigen/TES-26 Protein, Canine (P.pastoris, His) is a recombinant canine 26 kDa secreted antigen/TES-26 Protein expressed in P.pastoris with a His tag at the N-terminus. Recombinant TES-26 is a potential diagnostic candidate antigen for human toxocarosis caused by migrating T. canis larvae.

HY-P74552

	SFRP4 Protein, Human (CHO, His) secreted frizzled-related protein 4; sFRP-4; FrpHE; FRPHE	Human	CHO
	The SFRP4 protein is a member of the soluble Frizzled-related protein (sFRP) and regulates Wnt signaling by directly interacting with Wnt. It has similar functions to other sFRPs and contributes to the regulation of cell growth and differentiation in specific cell types. SFRP4 Protein, Human (CHO, His) is the recombinant human-derived SFRP4 protein, expressed by CHO , with C-His labeled tag.

HY-P74551

	SFRP4 Protein, Human (HEK293, His) 1 Publications Verification secreted frizzled-related protein 4; sFRP-4; FrpHE; FRPHE	Human	HEK293
	The SFRP4 protein is a member of the soluble Frizzled-related protein (sFRP) and regulates Wnt signaling by directly interacting with Wnt. It has similar functions to other sFRPs and contributes to the regulation of cell growth and differentiation in specific cell types. SFRP4 Protein, Human (HEK293, His) is the recombinant human-derived SFRP4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74550

	SFRP4 Protein, Mouse (HEK293, His) secreted frizzled-related protein 4; sFRP-4; FrpHE; FRPHE	Mouse	HEK293
	SFRP4 Protein, a soluble frizzled-related protein, directly interacts with Wnts, modulating Wnt signaling. It regulates cell growth and differentiation, impacting bone morphogenesis. In the adult uterus, SFRP4 serves as a regulator, potentially increasing apoptosis during ovulation via FZ1/FZ4/WNT4 signaling modulation. Additionally, it exhibits phosphaturic effects by inhibiting sodium-dependent phosphate uptake specifically. SFRP4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SFRP4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71281

	SECTM1 Protein, Human (HEK293, His) secreted and Transmembrane protein 1; protein K-12; SECTM1; K12	Human	HEK293
	SECTM1 Protein potentially influences thymocyte signaling, indicating a role in thymic regulatory mechanisms. Its interaction with CD7 suggests involvement in cellular processes, potentially influencing thymocyte-associated signaling pathways. SECTM1's significance in thymocyte function and interaction with CD7 hints at a role in modulating immune responses and cellular communication within the thymic microenvironment. SECTM1 Protein, Human (HEK293, His) is the recombinant human-derived SECTM1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73420

	SPARC Protein, Rat (HEK293, His) SPARC; BM-40; Osteonectin; ON; secreted protein Acidic and Rich in Cysteine	Rat	HEK293
	SPARC protein is involved in the regulation of cell growth and may play a regulatory role by affecting the interaction of extracellular matrix and cytokines. SPRC protein can bind calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. It has two calcium binding sites: one is an acidic domain that can bind 5-8 Ca²⁺ with low affinity, and the other is an EF-hand loop that can bind Ca²⁺ ions with high affinity. SPARC Protein, Rat (HEK293, His) is the recombinant rat-derived SPARC protein, expressed by HEK293 , with C-His labeled tag.

HY-P73413

	SFRP1 Protein, Mouse (CHO, His) 1 Publications Verification FRP1; FrzA; SARP-2; secreted frizzled-related protein 1; sFRP1	Mouse	CHO
	SFRP1 Protein is a secreted glycoprotein member of the SFRP family.SFRP1 Protein can act as an inhibitor of Wnt signaling and is capable of resisting vascular cell proliferation.SFRP1 Protein, Mouse (CHO, His) is the recombinant mouse-derived SFRP1 protein, expressed by CHO , with C-10*His labeled tag.

HY-P74553

	SFRP2 Protein, Mouse (HEK293, His) secreted frizzled-related protein 2; FRP-2; SARP-1; FKSG12	Mouse	HEK293
	SFRP2 protein has multiple functions such as Wnt protein binding and receptor ligand activity, and regulates gene expression and signal transduction.It functions upstream in animal organ development, signal transduction, and regulation of endopeptidase activity.SFRP2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SFRP2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P79222

	Osteopontin/OPN Protein, Rat (CHO, His) 2 Publications Verification Osteopontin; Spp1; Bone sialoprotein 1; secreted phosphoprotein 1; SPP-1; 2b7; secreted Phosphoprotein 1 [BNSP]	Rat	CHO
	Osteopontin/OPN Protein, a key non-collagenous bone protein, strongly binds to hydroxyapatite, crucial for the mineralized matrix.It likely plays a vital role in mediating cell-extracellular matrix interactions.Additionally, as a cytokine, OPN stimulates interferon-gamma and interleukin-12 production, while inhibiting interleukin-10, pivotal for the type I immunity pathway.Osteopontin/OPN Protein, Rat (CHO, His) is the recombinant rat-derived Osteopontin/OPN protein, expressed by CHO , with C-6*His labeled tag.

HY-P74554

	SFRP1 Protein, Human (HEK293, His) 2 Publications Verification FRP1; FrzA; SARP-2; secreted frizzled-related protein 1; sFRP1	Human	HEK293
	SFRP1 protein is a soluble Frizzled-related protein (sFRP) that regulates Wnt signaling by directly interacting with Wnt, affecting cell growth and differentiation. Notably, it reduces intracellular β-catenin levels and affects Wnt pathway components. SFRP1 Protein, Human (HEK293, His) is the recombinant human-derived SFRP1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75780

	FRZB Protein, Human (HEK293, His) secreted frizzled-related protein 3; sFRP-3; Frezzled; FrzB-1; FRZB; SFRP3	Human	HEK293
	FRZB protein is a soluble Frizzled-related protein (sFRP) that modulates Wnt signaling by directly interacting with Wnt, thereby regulating cell growth and differentiation. FRZB, also known as SFRP3, plays a key role in limb skeletogenesis as a Wnt8 signaling antagonist. FRZB Protein, Human (HEK293, His) is the recombinant human-derived FRZB protein, expressed by HEK293 , with C-His labeled tag.

HY-P76958

	GPHA2 Protein, Human (HEK293, His) Glycoprotein hormone alpha-2; Putative secreted protein Zsig51; GPA2; ZSIG51	Human	HEK293
	GPHA2 acts as a heterodimeric glycoprotein hormone together with GPHB5 to form a complex that binds and activates the thyroid-stimulating hormone receptor (TSHR), thereby triggering elevated cAMP production. This protein complex plays a key role in the regulation of thyroid cell metabolism, controlling the basic metabolic processes of thyroid cells. GPHA2 Protein, Human (HEK293, His) is the recombinant human-derived GPHA2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76959

	GPHA2 Protein, Human (HEK293, Fc) Glycoprotein hormone alpha-2; Putative secreted protein Zsig51; GPA2; ZSIG51	Human	HEK293
	GPHA2 acts as a heterodimeric glycoprotein hormone together with GPHB5 to form a complex that binds and activates the thyroid-stimulating hormone receptor (TSHR), thereby triggering elevated cAMP production. This protein complex plays a key role in the regulation of thyroid cell metabolism, controlling the basic metabolic processes of thyroid cells. GPHA2 Protein, Human (HEK293, Fc) is the recombinant human-derived GPHA2 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P71094

	SPARC Protein, Human (HEK293, His) 1 Publications Verification SPARC; Basement-Membrane protein 40; BM-40; Osteonectin; ON; secreted protein Acidic and Rich in Cysteine; SPARC; ON	Human	HEK293
	SPARC proteins are essential for lipid transport and are involved in the production, transformation, and clearance of plasma lipoproteins. It interacts with different particles, shows a preference for HDL, and binds to cellular receptors such as LDLR and VLDLR to promote the uptake of APOE-containing lipoproteins. SPARC Protein, Human (HEK293, His) is the recombinant human-derived SPARC protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73680

	Resistin Protein, Mouse (HEK293, Fc) Resistin; Adipose tissue-specific secretory factor; Cysteine-rich secreted protein FIZZ3; FIZZ3; ADSF; RSTN; RETN	Mouse	HEK293
	Resistin hormone inhibits insulin's efficacy in promoting glucose uptake into adipose cells, potentially linking obesity and diabetes. Structurally, it forms stabilizing disulfide linkages as a homodimer. The interplay between resistin and insulin reveals complex molecular mechanisms in metabolic regulation, providing insights into how resistin may contribute to the pathophysiological connections between obesity and diabetes. Resistin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Resistin protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P78771

	AG-2 Protein, Mouse (HEK293, His) Anterior gradient protein 2 homolog; AG-2; hAG-2; HPC8; secreted cement gland protein XAG-2 homolog; AGR2	Mouse	HEK293
	AG-2 protein is essential for the post-transcriptional synthesis and secretion of MUC2, a key component of mucus.It plays an important role in intestinal cell mucus production and is considered a proto-oncogene with potential effects on cell migration, differentiation and growth.AG-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived AG-2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73546

	VISTA/B7-H5 Protein, Rat (HEK293, Fc) Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Rat	HEK293
	VISTA/B7-H5 protein, an immunoregulatory receptor, inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling. It also stimulates MMP14-mediated MMP2 activation, suggesting a role in matrix metalloproteinase processes. These roles highlight the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics. VISTA/B7-H5 Protein, Rat (HEK293, Fc) is the recombinant rat-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73547

	VISTA/B7-H5 Protein, Mouse (HEK293, Fc) Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Mouse	HEK293
	VISTA/B7-H5 Protein is a type I transmembrane protein expressed primarily in white blood cells that inhibits T cell function. VISTA/B7-H5 Protein promotes embryonic stem cell differentiation by inhibiting BMP4 signaling and stimulates MMP14 mediated MMP2 activation. VISTA/B7-H5 Protein is highly expressed in tumors. VISTA/B7-H5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70962

	VISTA/B7-H5 Protein, Cynomolgus (HEK293, His) Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Cynomolgus	HEK293
	VISTA/B7-H5 Protein is a B7 family member that maintains T cell and myeloid quiescence and is a promising target for combination cancer immunotherapy. VISTA not only acts as a ligand expressed on antigenpresenting cells, but also functions as a receptor on T cells. VISTA inhibits T cell activation, proliferation, and cytokine production. VISTA/B7-H5 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73482

	VISTA/B7-H5 Protein, Cynomolgus (HEK293, Fc) Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Cynomolgus	HEK293
	VISTA/B7-H5 Protein is a B7 family member that maintains T cell and myeloid quiescence and is a promising target for combination cancer immunotherapy. VISTA not only acts as a ligand expressed on antigenpresenting cells, but also functions as a receptor on T cells. VISTA inhibits T cell activation, proliferation, and cytokine production. VISTA/B7-H5 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70463

	I-309/CCL1 Protein, Human C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-secreted protein I-309; CCL1; SCYA1	Human	E. coli
	CCL1 Protein, Human is a cytokine that mediates inflammatory immune responses, viral infections, and tumorigenesis by interacting with the CCR8 chemokine receptor on the cell surface and attracting monocytes, natural killer cells, and immature B-cell nuclear dendritic cells. I-309/CCL1 Protein, Human is a recombinant human CCL1 (K24-K96) expressed by E. coli.

HY-P73544

	VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, His) Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Rhesus Macaque	HEK293
	VISTA/B7-H5 protein is an immune regulatory receptor that can inhibit the activation of T cells and regulate immune responses as a ligand and receptor. VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73545

	VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, Fc) Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Rhesus Macaque	HEK293
	VISTA/B7-H5 protein is an immune regulatory receptor that can inhibit the activation of T cells and regulate immune responses as a ligand and receptor. VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P79064

	Endo S2 Protein, S. pyogenes (His) secreted Endo-beta-N-acetylglucosaminidase (EndoS); endoS; Spy49_1414c; Endo-beta-N-acetylglucosaminidase S2	Others	E. coli
	Endo S2, secreted by Streptococcus pyogenes, deglycosylates the conserved N-linked glycan at Asn297 on IgG Fc to eliminate its effector functions and evade the immune system. EndoS2 specifically hydrolyzes diverse glycans on the Fc region of IgG antibodies using a mechanism that relies on its glycoside hydrolase domain and a coevolved carbohydrate-binding module. Endo S2 Protein, S. pyogenes (His) is the recombinant Endo S2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70499

	Osteopontin/OPN Protein, Human (HEK293, His) Maximum Cited Publications 8 Publications Verification Osteopontin; Bone Sialoprotein 1; Nephropontin; secreted Phosphoprotein 1; SPP-1; Urinary Stone protein; Uropontin; SPP1; BNSP; OPN	Human	HEK293
	Osteopontin/OPN is a secretory glycophosphoprotein belonging to the SIBLING family. It contains RGD sequences and phosphorylation sites and can bind to integrins α_vβ₃, α₄β₁ and CD44 receptors. Osteopontin/OPN regulates cell adhesion and migration through receptor-mediated regulation, activates MAPK/ERK and PI3K-AKT to promote tumor invasion, and upregulates TIMP-1/2 to inhibit MMPs and protect cartilage. Osteopontin/OPN can be used in the study of osteoarthritis, liver cancer, etc.

HY-P78936

	VISTA/B7-H5 Protein, Human (Biotinylated, HEK293, His-Avi) Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Human	HEK293
	VISTA/B7-H5 protein, an immunoregulatory receptor, inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling. It also stimulates MMP14-mediated MMP2 activation, suggesting a role in matrix metalloproteinase processes. These roles highlight the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics. VISTA/B7-H5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P704262

	CD38 Protein, Human (HEK293, mFc) VISTA; B7-H5; Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Human	HEK293
	The CD38 protein plays a key role in cell signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a critical second messenger for glucose-induced insulin secretion. It also promotes the synthesis of the calcium mobilizer niacin-adenine dinucleotide phosphate (NAADP+). CD38 Protein, Human (HEK293, mFc) is the recombinant human-derived CD38 protein, expressed by HEK293, with C-mFc labeled tag.

HY-P700200AF

	Animal-Free IL-24 Protein, Mouse (His) Interleukin-24; IL-4-induced secreted protein; Melanoma differentiation-associated gene 7 protein (MDA-7); Th2-specific cytokine FISP; Il24; Mda7	Mouse	E. coli
	IL-24 Protein, a crucial immune regulatory cytokine, plays a pivotal role in modulating immune responses. Animal-Free IL-24 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-24 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P704667

	I-309/CCL1 Protein, Human (HEK293) C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-secreted protein I-309; CCL1; SCYA1	Human	HEK293
	I-309/CCL1 Protein, Human (HEK293) is the recombinant human-derived I-309/CCL1 protein, expressed by HEK293, with tag free tag.

HY-P704666

	I-309/CCL1 Protein, Human (HEK293, mFc) C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-secreted protein I-309; CCL1; SCYA1	Human	HEK293
	I-309/CCL1 Protein, Human (HEK293, mFc) is the recombinant human-derived I-309/CCL1 protein, expressed by HEK293, with C-mFc tag.

HY-P71786

	Osteopontin/OPN Protein, Mouse (P.pastoris, His) 3 Publications Verification Spp1; Eta-1; Op; Spp-1; Osteopontin; 2AR; Minopontin; secreted phosphoprotein 1; SPP-1	Mouse	P. pastoris
	Osteopontin/OPN Protein, a crucial non-collagenous bone protein, binds strongly to hydroxyapatite, integral to the mineralized matrix.It likely plays a vital role in mediating cell-extracellular matrix interactions.Moreover, as a cytokine, OPN efficiently induces interferon-gamma and interleukin-12 production while inhibiting interleukin-10, pivotal in promoting type I immunity.Osteopontin/OPN Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Osteopontin/OPN protein, expressed by P.pastoris , with N-6*His labeled tag.

HY-P75927

	MGAT5 Protein, Human (HEK293, His) Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; GNT-V; secreted GNT-V; MGAT5; GGNT5	Human	HEK293
	The MGAT5 protein regulates the cytoskeleton, adhesion, migration, and signaling. MGAT5 Protein, Human (HEK293, His) is the recombinant human-derived MGAT5 protein, expressed by HEK293 , with C-His labeled tag.

HY-P70983

	VISTA/B7-H5 Protein, Human (HEK293, His) VISTA; B7-H5; Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Human	HEK293
	VISTA/B7-H5 protein, an immunoregulatory receptor, inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling. It also stimulates MMP14-mediated MMP2 activation, suggesting a role in matrix metalloproteinase processes. These roles highlight the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics. VISTA/B7-H5 Protein, Human (HEK293, His) is the recombinant human-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P705140

	I-309/CCL1 Protein, Human (Biotinylated, HEK293, His-Avi) C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-secreted protein I-309; CCL1; SCYA1	Human	HEK293

HY-P702605

	CFP-10 Protein, Mycobacterium tuberculosis (His) esxB; cfp10; lhp; mtsA10; MT3988ESAT-6-like protein EsxB; 10 kDa culture filtrate antigen CFP-10; secreted antigenic protein MTSA-10; Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	Others	E. coli
	CFP-10 Protein, Mycobacterium tuberculosis (His) is the recombinant CFP-10, expressed by E. coli , with N-6*His labeled tag.

HY-P71674

	Semaphorin-3F/SEMA3F Protein, Human (HEK293, His-Myc) sema domain immunoglobulin domain Ig short basic domain secreted 3F; sema domain immunoglobulin domain Ig short basic domain secreted semaphorin 3F; Sema III/F; Sema IV; SEMA-IV; SEMA3F; SEMA4; SemaIII/F; SemaIV; SEMAK; Semaphorin IV; Semaphorin-3F; Semaphorin3F; SemaphorinIV	Human	HEK293
	Semaphorin-3F/SEMA3F proteins may play a role in cell motility and adhesion, suggesting involvement in fundamental cellular processes related to movement and interactions. The precise mechanisms and context by which SEMA3F regulates cell motility and adhesion are areas of interest, highlighting its potential significance in cell dynamics. Semaphorin-3F/SEMA3F Protein, Human (HEK293, His) is the recombinant human-derived Semaphorin-3F/SEMA3F protein, expressed by HEK293 , with N-6*His, N-Myc labeled tag.

HY-P701071

	Osteopontin/OPN Protein, Cynomolgus (HEK293, His) secreted phosphoprotein 1; Osteopontin; Bone sialoprotein 1; Nephropontin; SPP-1; BNSP; OPN; SPP1; Uropontin; BSP-1; ETA-1; BSPI	Cynomolgus	HEK293
	Osteopontin/OPN protein is an important member of the osteopontin family and plays a key role in cell adhesion, immune response regulation, and tissue mineralization. Osteopontin has conserved features within the family and its multifunctional properties contribute to both homeostasis and pathological conditions. Osteopontin/OPN Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Osteopontin/OPN protein, expressed by HEK293 , with C-His labeled tag.

HY-P703697

	CLEC11A/SCGF-alpha Protein, Rat (HEK293, His) C-type lectin domain family 11 member A; Lymphocyte secreted C-type lectin; Osteolectin; Stem cell growth factor; Clec11a	Rat	HEK293
	CLEC11A/SCGF-alpha Protein, Rat (HEK293, His) is the recombinant rat-derived CLEC11A/SCGF-alpha protein, expressed by HEK293, with C-His tag.

HY-P79138

	PSP94/MSMB Protein, Human (His) Beta-microseminoprotein; MSMB; Immunoglobulin-binding factor; IGBF; PN44; Prostate secreted seminal plasma protein; Prostate secretory protein of 94 amino acids; PSP-94; PSP94; Seminal plasma beta-inhibin; PRSP; Prostate Secretory protein of 94 Amino Acid	Human	E. coli
	PSP94/MSMB protein forms homodimers and interacts with PI16. PSP94/MSMB Protein, Human (His) is the recombinant human-derived PSP94/MSMB protein, expressed by E. coli , with C-His labeled tag.

HY-P702549

	sFRP-3 Protein, Mouse (HEK293, His) FIZ; FREOS1; Frezzled; Fritz; Frizzled-related protein 1; frizzled-related protein; FRP; FRP-3; FRZB; Frzb1; FRZB-1; FRZB1sFRP-3; FRZB-PEN; FZRB; hFIZ; secreted frizzled-related protein 3; sFRP3; sFRP-3; SFRP3frezzled; SRFP3frizzled homolog-related	Mouse	HEK293
	The sFRP-3 protein is a soluble Frizzled-related protein that modulates Wnt signaling by directly interacting with Wnt, thereby regulating cell growth and differentiation. Known as FRZB, it acts as a Wnt8 signaling antagonist with crucial effects on limb skeletogenesis. sFRP-3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived sFRP-3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P704521

	GPR15L Protein, Human (His, Myc) GPR15L; C10orf99; UNQ1833/PRO3446; protein GPR15L; Antimicrobial peptide with 57 amino acid residues; AP-57; Antimicrobial peptide-57; Colon-derived SUSD2 binding factor; CSBF; secreted protein C10orf99	Human	E. coli
	GPR15L Protein, Human (His, Myc) is the recombinant human-derived GPR15L protein, expressed by E. coli, with N-10*His & C-Myc tag.

HY-P71913

	TL1A/TNFSF15 Protein, Human MGC129934; MGC129935; TL1 A; tl1; tl1a; tnf ligand related molecule 1; TNF ligand-related molecule 1; tnf superfamily ligand tl1a; TNF15_HUMAN; TNFSF15; Tumor necrosis factor ligand; superfamily member 15; Tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15, secreted form;	Human	E. coli
	TL1A/TNFSF15 Protein, the receptor for TNFRSF25 and TNFRSF6B, activates NF-kappa-B and promotes caspase activation, leading to apoptosis. It also inhibits vascular endothelial growth and angiogenesis in vitro. Operating as a homotrimer, it plays a crucial role in diverse cellular processes, including immune response and apoptosis regulation. TL1A/TNFSF15 Protein, Human is the recombinant human-derived TL1A/TNFSF15 protein, expressed by E. coli , with tag free.

HY-P702569

	TL1A/TNFSF15 Protein, Human (Biotinylated, HEK293, Avi-His) MGC129934; MGC129935; TL1 A; tl1; tl1a; tnf ligand related molecule 1; TNF ligand-related molecule 1; tnf superfamily ligand tl1a; TNF15_HUMAN; TNFSF15; Tumor necrosis factor ligand; superfamily member 15; Tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15, secreted form;	Human	HEK293
	TL1A/TNFSF15 Protein, the receptor for TNFRSF25 and TNFRSF6B, activates NF-kappa-B and promotes caspase activation, leading to apoptosis. It also inhibits vascular endothelial growth and angiogenesis in vitro. Operating as a homotrimer, it plays a crucial role in diverse cellular processes, including immune response and apoptosis regulation. TL1A/TNFSF15 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived TL1A/TNFSF15 protein, expressed by HEK293 , with N-10*His, N-Avi labeled tag.

HY-P702569A

	TL1A/TNFSF15 Protein, Human (Biotinylated, HEK293, Avi-His, solution) MGC129934; MGC129935; TL1 A; tl1; tl1a; tnf ligand related molecule 1; TNF ligand-related molecule 1; tnf superfamily ligand tl1a; TNF15_HUMAN; TNFSF15; Tumor necrosis factor ligand; superfamily member 15; Tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15, secreted form;	Human	HEK293
	TL1A/TNFSF15 Protein, the receptor for TNFRSF25 and TNFRSF6B, activates NF-kappa-B and promotes caspase activation, leading to apoptosis. It also inhibits vascular endothelial growth and angiogenesis in vitro. Operating as a homotrimer, it plays a crucial role in diverse cellular processes, including immune response and apoptosis regulation. TL1A/TNFSF15 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived TL1A/TNFSF15 protein, expressed by HEK293 , with N-10*His, N-Avi labeled tag.

HY-P71981

	TL1A/TNFSF15 Protein, Human (O95150-2, HEK293, His) MGC129934; MGC129935; TL1 A; tl1; tl1a; tnf ligand related molecule 1; TNF ligand-related molecule 1; tnf superfamily ligand tl1a; TNF15_HUMAN; TNFSF15; Tumor necrosis factor ligand; superfamily member 15; Tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15, secreted form; Vascular endothelial cell growth inhibitor; Vascular endothelial growth inhibitor 192a; Vascular endothelial growth inhibitor; vegi; VEGI192A	Human	HEK293
	TL1A/TNFSF15 Protein, the receptor for TNFRSF25 and TNFRSF6B, activates NF-kappa-B and promotes caspase activation, leading to apoptosis. It also inhibits vascular endothelial growth and angiogenesis in vitro. Operating as a homotrimer, it plays a crucial role in diverse cellular processes, including immune response and apoptosis regulation. TL1A/TNFSF15 Protein, Human (O95150-2, HEK293, His) is the recombinant human-derived TL1A/TNFSF15 protein, expressed by HEK293 , with labeled tag.

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Host:	Mouse (5) Rabbit (14)
Reactivity:	Human (19) Rat (6) Mouse (7)
Application:	IHC-P (18) ICC/IF (7) IF-Tissue (2) IP (2) IHC-F (4) WB (13) FC (1) ELISA (6)
Isotype:	IgG (14) IgG1 (3) IgG1,IgG/Kappa (1) IgG/Kappa (1)
Conjugation:	Non-conjugated (19) Biotin (4)
Clonality:	Polyclonal (1) polyclonal (1) Monoclonal (13) Recombinant (7)
Modification:	Unmodified (15)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83566

	SFRP1 Antibody (YA3311) Frizzled related protein 1; FRP1; FrzA; SARP2; secreted apoptosis related protein 2; secreted frizzled related protein 1; SFRP1	WB, IHC-P, ICC/IF	Human
	SFRP1 Antibody (YA3311) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SFRP1.

HY-P81457

	SPARC Antibody (YA1202) SPARC; ON; SPARC; Basement-membrane protein 40; BM-40; Osteonectin; ON; secreted protein acidic and rich in cysteine	IHC-P	Human
	SPARC Antibody (YA1202) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SPARC.

HY-P87077

	SMOC2 Antibody (YA6770) bA270C4A.1 antibody; bA37D8.1 (secreted modular calcium binding protein 2) antibody; bA37D8.1 antibody; dJ421D16.1 (novel thyroglobulin type 1 repeat containing protein) antibody; dJ421D16.1 antibody; MST117 antibody; MSTP117 antibody; MSTP140 antibody; secreted modular calcium binding protein 2 antibody; secreted modular calcium-binding protein 2 antibody	WB, IHC-P	Human, Mouse, Rat
	SMOC2 Antibody (YA6770) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SMOC2.

HY-P81457A

	SPARC Antibody (YA1202)(PBS only) SPARC; ON; SPARC; Basement-membrane protein 40; BM-40; Osteonectin; ON; secreted protein acidic and rich in cysteine	IHC-P	Human
	SPARC Antibody (YA1202) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SPARC.

HY-P86050

	Glypican 3 Antibody (YA5742) Glypican-3; GTR2-2; Intestinal protein OCI-5; MXR7; [Cleaved into: secreted glypican-3]	IHC-P, ELISA	Human
	Glypican 3 Antibody (YA5742) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Glypican 3.

HY-P80771

	Osteopontin Antibody 1 Publications Verification SPP1; BNSP; OPN; PSEC0156; Osteopontin; Bone sialoprotein 1; Nephropontin; secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin	WB, IHC-P, ELISA	Human, Mouse, Rat
	Osteopontin Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Osteopontin.

HY-P82034

	Anterior Gradient 2 Antibody (YA1779) Anterior gradient protein 2 homolog; AG-2; hAG-2; HPC8; secreted cement gland protein XAG-2 homolog; AGR2; AG2; GOB4; XAG2	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Rat
	Anterior Gradient 2 Antibody (YA1779) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Anterior Gradient 2.

HY-P82034A

	Anterior Gradient 2 Antibody (YA1779)(PBS only) Anterior gradient protein 2 homolog; AG-2; hAG-2; HPC8; secreted cement gland protein XAG-2 homolog; AGR2; AG2; GOB4; XAG2	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Rat
	Anterior Gradient 2 Antibody (YA1779) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Anterior Gradient 2.

HY-P810514

	Wnt2 Antibody Int 1 related protein, INT1L 1, INT1L1, IRP, IRP protein, ONCOGENE INT1 LIKE 1, protein Wnt-2, secreted growth factor, Wingless type MMTV integration site family member 2, WNT2	WB, IHC-P	Human, Mouse
	Wnt2 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Wnt2.

HY-P810729

	Osteopontin Antibody (YA9973) Eta-1, Op, Spp-1, Spp1, Osteopontin, 2AR, Bone sialoprotein 1, Calcium oxalate crystal growth inhibitor protein, Early T-lymphocyte activation 1 protein, Minopontin, secreted phosphoprotein 1, SPP-1	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Osteopontin Antibody (YA9973) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to Osteopontin Antibody.

HY-P85933

	Melanoma gp100 Antibody (YA5625) 95 kDa melanocyte specific secreted glycoprotein; 95 kDa melanocyte-specific secreted glycoprotein; D12S53E; gp100; M-beta; ME20; ME20 M/ME20 S; ME20-M; ME20-S; ME20M; ME20M/ME20S; ME20S; Melanocyte lineage specific antigen GP100; Melanocyte protein mel 17; Melanocyte protein Pmel 17; Melanocyte protein Pmel 17 precursor; Melanocytes lineage-specific antigen GP100; Melanoma associated ME20 antigen; Melanoma gp100; Melanoma-associated ME20 antigen; Melanosomal matrix protein 17; Melanosomal matrix protein17; P1; p100; p26; PMEL 17; PMEL; PMEL_HUMAN; PMEL17; Premelanosome protein; secreted melanoma-associated ME20 antigen; SI; SIL; SILV; Silver; Mouse homolog; like; Silver homolog; Silver locus protein homolog; Silver, Mouse, homolog of	IHC-P, WB, ICC/IF, ELISA	Human, Mouse
	Melanoma gp100 Antibody (YA5625) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Melanoma gp100.

HY-P86057

	Melanoma gp100 Antibody (YA5749) 95 kDa melanocyte specific secreted glycoprotein; 95 kDa melanocyte-specific secreted glycoprotein; D12S53E; gp100; M-beta; ME20; ME20 M/ME20 S; ME20-M; ME20-S; ME20M; ME20M/ME20S; ME20S; Melanocyte lineage specific antigen GP100; Melanocyte protein mel 17; Melanocyte protein Pmel 17; Melanocyte protein Pmel 17 precursor; Melanocytes lineage-specific antigen GP100; Melanoma associated ME20 antigen; Melanoma gp100; Melanoma-associated ME20 antigen; Melanosomal matrix protein 17; Melanosomal matrix protein17; P1; p100; p26; PMEL 17; PMEL; PMEL_HUMAN; PMEL17; Premelanosome protein; secreted melanoma-associated ME20 antigen; SI; SIL; SILV; Silver; mouse homolog; like; Silver homolog; Silver locus protein homolog; HMB45;	IHC-P, ELISA	Human, Mouse
	Melanoma gp100 Antibody (YA5749) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Melanoma gp100.

HY-P83228

	Wnt2 Antibody (YA2973) Int 1 related protein; INT1L 1; INT1L1; IRP; IRP protein; ONCOGENE INT1 LIKE 1; protein Wnt-2; secreted growth factor; Wingless type MMTV integration site family member 2; WNT2	WB	Human, Mouse, Rat
	Wnt2 Antibody (YA2973) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Wnt2.

HY-P86670

	Osteopontin Antibody (YA6362) BNSP; Bone sialoprotein 1; BSP I; BSPI; Early T lymphocyte activation 1; ETA 1; ETA1; MGC110940; Nephropontin; OPN; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; OSTP_HUMAN; secreted phosphoprotein 1(osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1; SPP 1; SPP-1; SPP1; SPP1/CALPHA1 fusion; Urinary stone protein; Uropontin.	IHC-P, WB, IHC-F, IF-Tissue	Human
	Osteopontin Antibody (YA6362) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Osteopontin.

HY-P86670A

	Osteopontin Antibody (YA6362)(PBS only) BNSP; Bone sialoprotein 1; BSP I; BSPI; Early T lymphocyte activation 1; ETA 1; ETA1; MGC110940; Nephropontin; OPN; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; OSTP_HUMAN; secreted phosphoprotein 1(osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1; SPP 1; SPP-1; SPP1; SPP1/CALPHA1 fusion; Urinary stone protein; Uropontin.	IHC-P, WB, IHC-F, IF-Tissue	Human
	Osteopontin Antibody (YA6362) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Osteopontin.

HY-P81531

	VISTA Antibody (YA1276) VSIR; PP2135, UNQ730/PRO1412; C10orf54, SISP1; VISTA; V-type immunoglobulin domain-containing suppressor of T-cell activation; Platelet receptor Gi24; Stress-induced secreted protein-1; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor	IHC-P	Human
	VISTA Antibody (YA1276) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VISTA.

HY-P81531A

	VISTA Antibody (YA1276)(PBS only) VSIR; PP2135, UNQ730/PRO1412; C10orf54, SISP1; VISTA; V-type immunoglobulin domain-containing suppressor of T-cell activation; Platelet receptor Gi24; Stress-induced secreted protein-1; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor	IHC-P	Human
	VISTA Antibody (YA1276) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VISTA.

HY-P85917

	Glypican 3 Antibody (YA5609) DGSX; Glypican proteoglycan 3; Glypican-3 [Precursor]; Gpc3; GPC3_HUMAN; GTR2 2; GTR2-2; Heparan sulphate proteoglycan; Intestinal protein OCI 5; Intestinal protein OCI-5; MXR7; OCI 5; OCI-5; OCI5; SDYS; secreted glypican-3; SGB; SGBS; SGBS1	IHC-P, WB, ICC/IF, ELISA	Human
	Glypican 3 Antibody (YA5609) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Glypican 3.

HY-P85940

	Glypican 3 Antibody (YA5632) DGSX; Glypican proteoglycan 3; Glypican-3 [Precursor]; Gpc3; GPC3_HUMAN; GTR2 2; GTR2-2; Heparan sulphate proteoglycan; Intestinal protein OCI 5; Intestinal protein OCI-5; MXR7; OCI 5; OCI-5; OCI5; SDYS; secreted glypican-3; SGB; SGBS; SGBS1	IHC-P, WB, ICC/IF, ELISA	Human
	Glypican 3 Antibody (YA5632) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Glypican 3.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-174662

Human IFNG mRNA		mRNA Interferon & Receptors
Human IFNG mRNA encodes the human interferon gamma (IFNG) protein, a member of the type II interferon class. IFNG is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections.

HY-177819

DTA-64 sodium		Aptamers
DTA-64 sodium is a aptamer targeted DEK. It significantly reduces joint inflammation in zymosan-induced arthritis mouse model and greatly impairs the ability of neutrophils to form neutrophil extracellular traps (NETs). DEK is a secreted protein abundant

HY-174772

Human CCL1 mRNA		mRNA Chemokine & Receptors
Human CCL1 mRNA encodes the human C-C motif chemokine ligand 1 (CCL1) protein, a member of the CC subfamily. CCL1 is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils.

HY-174533

Human TGFB2 mRNA		mRNA
Human TGFB2 mRNA encodes the human transforming growth factor beta 2 (TGFB2) protein, a secreted ligand of the TGF-beta superfamily. TGFB2 has suppressive effects on interleukin-2 dependent T-cell growth.

HY-174700

Human FGF21 mRNA		mRNA
Human FGF21 mRNA encodes the human fibroblast growth factor 21 (FGF21) protein, a member of the fibroblast growth factor (FGF) family. FGF21 is a secreted endocrine factor that functions as a major metabolic regulator. It stimulates the uptake of glucose in adipose tissue.

HY-174534

Human TGFB1 mRNA		mRNA
Human TGFB1 mRNA encodes the human transforming growth factor beta 1 (TGFB1) protein, a secreted ligand of the TGF-beta superfamily. TGFB1 can regulate cell proliferation, differentiation and growth, and also play a role in modulating expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha.

HY-174532

Human TGFB3 mRNA		mRNA
Human TGFB3 mRNA encodes the human transforming growth factor beta 3 (TGFB3) protein, a secreted ligand of the TGF-beta superfamily. TGFB3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing.

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