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Results for "

sulfonamide antibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (77) Apoptosis (3) Bacterial (82) Cytochrome P450 (3) Dihydrofolate reductase (DHFR) (2) DNA/RNA Synthesis (2) Drug Metabolite (2) Environmental Pollutants (6) Fungal (8) Isotope-Labeled Compounds (21) mTOR (2) Necroptosis (3) Nucleoside Antimetabolite/Analog (1) Parasite (17) Reactive Oxygen Species (ROS) (6) Reference Standards (22) α-synuclein (2)
By Research Areas:	Cancer (6) Cardiovascular Disease (2) Endocrinology (3) Infection (79) Inflammation/Immunology (17) Neurological Disease (3)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Antibiotic

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-B0322

Sulfamethoxazole Maximum Cited Publications 24 Publications Verification Ro 4-2130	Antibiotic Bacterial	Infection Cancer
Sulfamethoxazole (Ro 4-2130) is a sulfonamide *antibiotic* with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .

HY-B1218

Sulfaphenazole 10+ Cited Publications	Cytochrome P450 Antibiotic Bacterial Necroptosis Apoptosis	Infection Cardiovascular Disease
Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide *antibiotic* and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .

HY-B0242

Sulfanilamide 5 Publications Verification Sulphanilamide	Environmental Pollutants Antibiotic Bacterial	Infection
ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum .

HY-B0507

Sulfathiazole 5 Publications Verification	Environmental Pollutants Antibiotic Bacterial	Endocrinology Cancer
Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish .

HY-B0688

Dapsone 4 Publications Verification 4,4′-Diaminodiphenyl sulfone; DDS	Antibiotic Parasite Bacterial Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology
Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide *antibiotic* with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B0921

Succinylsulfathiazole 1 Publications Verification Succinylsulphathiazole	Antibiotic Bacterial Dihydrofolate reductase (DHFR) mTOR	Infection
Succinylsulfathiazole (Succinylsulphathiazole) is a long-acting sulfonamide antibiotic with localized gut-specific antibacterial activity and is orally active. Succinylsulfathiazole inhibits bacterial folate synthesis, reduces coliform counts, suppresses intestinal bacterial growth and vitamin biosynthesis, and depletes gut folate-producing bacteria. Succinylsulfathiazole modulates hepatic mTOR signaling, diminishes cecal fermentation, decreases hepatic folate levels and total folate excretion, elevates nitrogen excretion and reduces the fermentability of certain dietary fibers. Succinylsulfathiazole induces folate deficiency and triggers biotin- and folate-related nutritional deficiency symptoms in rats and C57BL/6 mice .

HY-B0273

Sulfadiazine 5+ Cited Publications	Bacterial Parasite Antibiotic	Infection
Sulfadiazine is a sulfonamide *antibiotic* with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research .

HY-B0322S

Sulfamethoxazole-d4 1 Publications Verification Ro 4-2130-d₄	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Sulfamethoxazole-d₄ (Ro 4-2130-d₄) is a deuterium labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide *antibiotic* with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .

HY-B1267

Sulfaguanidine 2 Publications Verification	Bacterial Antibiotic	Infection
Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery .

HY-B0337

Sulfadimethoxine 3 Publications Verification Sulphadimethoxine	Bacterial Antibiotic	Infection
Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections .

HY-B0212

Sulfapyridine 2 Publications Verification	Bacterial Antibiotic	Infection Inflammation/Immunology
Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits *recombinant P. carinii* dihydropteroate synthetase (DHPS) with an IC₅₀** of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities .

HY-B0322A

Sulfamethoxazole sodium Maximum Cited Publications 24 Publications Verification Ro 4-2130 sodium	Antibiotic Bacterial	Infection
Sulfamethoxazole (Ro 4-2130) sodium is a sulfonamide *antibiotic* with a widespread antibacterial activity. Sulfamethoxazole sodium inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole sodium can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .

HY-B0512

Sulfamerazine 4 Publications Verification RP2632	Antibiotic Bacterial α-synuclein	Infection Neurological Disease
Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide *antibiotic* and α-synuclein inhibitor with human α-synuclein K_D of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection .

HY-B0273A

Sulfadiazine sodium 5+ Cited Publications	Bacterial Parasite Antibiotic	Infection
Sulfadiazine sodium is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research .

HY-B1282

Sulfaquinoxaline 2 Publications Verification	Environmental Pollutants Antibiotic Parasite Bacterial	Infection
Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections .

HY-B0946

Sulfamonomethoxine 1 Publications Verification	Antibiotic Bacterial	Infection
Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-B0213

Sulfameter 2 Publications Verification Sulfametoxydiazine; 5-Methoxysulfadiazine; NSC 683528	Antibiotic Bacterial	Infection
Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections .

HY-B1497

Silver sulfadiazine 1 Publications Verification AgSD	Bacterial DNA/RNA Synthesis Antibiotic	Infection
Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication .

HY-N7123

Sulfacetamide 3 Publications Verification Sulphacetamide	Environmental Pollutants Antibiotic Bacterial Fungal	Infection Inflammation/Immunology
Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections .

HY-B1781

Sulfachloropyridazine 2 Publications Verification Sulfachlorpyridazine	Bacterial Antibiotic	Infection
Sulfachloropyridazine is a broad spectrum sulfonamide that can be used against both gram-positive and gram-negative aerobic bacteria as well as Chlamydia. Sulfachloropyridazine is also considered as a common pollutant in surface and groundwater. Sulfachloropyridazine via electro-Fenton is a model for sulfonamide antibiotics that are widespread in waters .

HY-B0337A

Sulfadimethoxine sodium 3 Publications Verification Sulphadimethoxine sodium	Bacterial Antibiotic	Infection
Sulfadimethoxine sodium (Sulphadimethoxine sodium) is a sulfonamide *antibiotic*. Sulfadimethoxine sodium causes a displacement of Thiopental in plasma protein binding in rats. Sulfadimethoxine sodium is used in a variety of infection studies including urinary tract infections .

HY-B1387

Sulfamethoxypyridazine	Antibiotic Bacterial	Inflammation/Immunology
Sulfamethoxypyridazine is an orally active and brain-penetrant sulfonamide *antibiotic. Sulfamethoxypyridazine exhibits antibacterial activity and inhibits growth of susceptible bacterial* strains. Sulfamethoxypyridazine can be used for the research of pyelonephritis, urinary tract infections, and dermatitis herpetiformis .

HY-B0322S1

Sulfamethoxazole-13C6 Ro 4-2130-¹³C₆	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Sulfamethoxazole- ¹³C₆ (Ro 4-2130- ¹³C₆) is a ¹³C labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide *antibiotic* with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .

HY-B0576

Sulfacetamide sodium 3 Publications Verification Sulphacetamide sodium	Antibiotic Bacterial Fungal	Infection Inflammation/Immunology
Sulfacetamide (Sulphacetamide) sodium is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide sodium has antifungal and antibacterial activities .

HY-B1282A

Sulfaquinoxaline sodium salt 2 Publications Verification	Bacterial Parasite Antibiotic	Infection
Sulfaquinoxaline sodium salt is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections .

HY-B0035S

Sulfamethazine-d4 Sulfadimidine-d₄; Sulfadimerazine-d₄	Bacterial	Infection
Sulfamethazine-d₄ (Sulfadimidine-d₄) is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections) .

HY-B0322R

Sulfamethoxazole (Standard) Ro 4-2130 (Standard)	Reference Standards Antibiotic Bacterial	Infection
Sulfamethoxazole (Standard) (Ro 4-2130 (Standard)) is the analytical standard of Sulfamethoxazole (HY-B0322). This product is intended for research and analytical applications. Sulfamethoxazole (Ro 4-2130) is a sulfonamide *antibiotic* with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.

HY-B0322AR

Sulfamethoxazole sodium (Standard) Ro 4-2130 sodium (Standard)	Reference Standards Antibiotic Bacterial	Infection Cancer
Sulfamethoxazole (Standard) (Ro 4-2130 (Standard)) sodium is the analytical standard of Sulfamethoxazole sodium (HY-B0322A). This product is intended for research and analytical applications. Sulfamethoxazole (Ro 4-2130) sodium is a sulfonamide *antibiotic* with a widespread antibacterial activity. Sulfamethoxazole sodium inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole sodium can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.

HY-B0273S

Sulfadiazine-d4	Bacterial	Infection
Sulfadiazine-d₄ is a deuterium labeled Sulfadiazine. Sulfadiazine is a sulfonamide antibiotic used for the treatment of toxoplasmosis .

HY-B0888

Sulfacetamide sodium monohydrate 3 Publications Verification Sulphacetamide sodium monohydrate	Antibiotic Bacterial Fungal	Infection Inflammation/Immunology
Sulfacetamide (Sulphacetamide) sodium monohydrate is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide sodium monohydrate has antifungal and antibacterial activities .

HY-16472

Sulfacytine	Antibiotic Bacterial	Infection
Sulfacytine is a short-acting sulfonamide *antibiotic. Sulfacytine is active against bacteria* and is an effective agent for the research of acute uncomplicated urinary tract infections .

HY-B0507S

Sulfathiazole-d4	Isotope-Labeled Compounds Antibiotic Bacterial	Endocrinology Cancer
Sulfathiazole-d₄ is a deuterium labeled Sulfathiazole. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish .

HY-B0035B

Sulfamethazine 100 µg/mL in acetonitrile Sulfadimidine 100 µg/mL in acetonitrile; Sulfadimerazine 100 µg/mL in acetonitrile	Antibiotic Bacterial	Infection
Sulfamethazine (Sulfadimidine) 100 µg/mL in acetonitrile is a brain-penetrant sulfonamide *antibiotic*. Sulfamethazine 100 µg/mL in acetonitrile inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine 100 µg/mL in acetonitrile can be used for research on bacterial infections .

HY-B0337B

Sulfadimethoxine 1000 µg/mL in methanol Sulphadimethoxine 1000 µg/mL in methanol	Antibiotic Parasite Environmental Pollutants	Infection
Sulfadimethoxine (Sulphadimethoxine) 1000 µg/mL in methanol is an orally active sulfonamide *antibiotic. Sulfadimethoxine 1000 µg/mL in methanol reduces Eimeria*-related mortality, weight loss, and lesions. Sulfadimethoxine 1000 µg/mL in methanol can be used for the research of avian coccidiosis .

HY-B0212R

Sulfapyridine (Standard)	Reference Standards Bacterial Antibiotic	Infection Inflammation/Immunology
Sulfapyridine (Standard) is the analytical standard of Sulfapyridine. This product is intended for research and analytical applications. Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits *recombinant P. carinii* dihydropteroate synthetase (DHPS) with an IC₅₀** of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities .

HY-B0322B

Sulfamethoxazole 1000 µg/mL in methanol 20+ Cited Publications Ro 4-2130 1000 µg/mL in methanol	Antibiotic Bacterial	Infection
Sulfamethoxazole (Ro 4-2130) 1000 μg/mL in methanol is a sulfonamide *antibiotic* with a widespread antibacterial activity. Sulfamethoxazole 1000 μg/mL in methanol inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole 1000 μg/mL in methanol can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .

HY-B0967

Phthalylsulfacetamide	Antibiotic Bacterial	Infection
Phthalylsulfacetamide is an orally active sulfonamide *antibiotic* and New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC₅₀ of 15.4 μM. Phthalylsulfacetamide stably binds to the active hydrolysis center of NDM-1, interacts with Zn²⁺, and interacts with key amino acid residues Val73 and His122 to inhibit enzyme activity. Phthalylsulfacetamide can be used for the research of Escherichia coli infection .

HY-B0688S2

Dapsone-13C12 4,4′-Diaminodiphenyl sulfone-¹³C₁₂; DDS-¹³C₁₂	Isotope-Labeled Compounds Antibiotic Parasite Bacterial Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology
Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B0273R

Sulfadiazine (Standard)	Reference Standards Bacterial Parasite Antibiotic	Infection
Sulfadiazine (Standard) is the analytical standard of Sulfadiazine. This product is intended for research and analytical applications. Sulfadiazine is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research .

HY-B1267R

Sulfaguanidine (Standard)	Reference Standards Bacterial Antibiotic	Infection
Sulfaguanidine (Standard) is the analytical standard of Sulfaguanidine. This product is intended for research and analytical applications. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery .

HY-B0337R

Sulfadimethoxine (Standard) Sulphadimethoxine (Standard)	Reference Standards Bacterial Antibiotic	Infection
Sulfadimethoxine (Standard) is the analytical standard of Sulfadimethoxine. This product is intended for research and analytical applications. Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections .

HY-B1781R

Sulfachloropyridazine (Standard) Sulfachlorpyridazine (Standard)	Reference Standards Bacterial Antibiotic	Infection
Sulfachloropyridazine (Standard) is the analytical standard of Sulfachloropyridazine. This product is intended for research and analytical applications. Sulfachloropyridazine is a broad spectrum sulfonamide that can be used against both gram-positive and gram-negative aerobic bacteria as well as Chlamydia. Sulfachloropyridazine is also considered as a common pollutant in surface and groundwater. Sulfachloropyridazine via electro-Fenton is a model for sulfonamide antibiotics that are widespread in waters .

HY-G0016

N-Acetyl dapsone MADDS; Monoacetyldapsone	Drug Metabolite	Others
N-Acetyl dapsone (MADDS) is the major metabolite of Dapsone (HY-B0688). Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities .

HY-B1267S1

Sulfaguanidine-13C6	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Sulfaguanidine- ¹³C₆ is the ¹³C₆ labeled Sulfaguanidine. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.

HY-N7123S

Sulfacetamide-d4 Sulphacetamide-d₄	Isotope-Labeled Compounds Bacterial Antibiotic Fungal	Infection Inflammation/Immunology
Sulfacetamide-d₄ (Sulphacetamide-d₄) is the deuterium labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities .

HY-B0946S

Sulfamonomethoxine-d4	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Sulfamonomethoxine-d₄ is a deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-B0242R

Sulfanilamide (Standard) Sulphanilamide (Standard)	Reference Standards Bacterial Antibiotic	Infection
Sulfanilamide (Standard) is the analytical standard of Sulfanilamide. This product is intended for research and analytical applications. ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum .

HY-121071

Ascamycin	Bacterial Nucleoside Antimetabolite/Analog Antibiotic	Infection
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against *Xanthomonas* species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for *Xanthomonas citri, Xanthomonas oryzae* and *Mycobacterium phlei*, respectively .

HY-B0688S

Dapsone-d8 4,4′-Diaminodiphenyl sulfone-d₈; DDS-d₈	Antibiotic Parasite Bacterial Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Dapsone-d₈ is a deuterium labeled Dapsone. Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with antibacterial, antigenic and anti-inflammatory activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone can be used as an anticonvulsant and also in the research of skin and glioblastoma diseases .

HY-B0512A

Sulfamerazine sodium RP2632 sodium	Antibiotic Bacterial α-synuclein	Infection Neurological Disease
Sulfamerazine (RP2632) sodium is a brain-penetrant and orally active sulfonamide *antibiotic* and α-synuclein inhibitor with human α-synuclein K_D of 352 μM. Sulfamerazine sodium inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine sodium inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine sodium can be used for the research of Parkinson’s disease and bacterial infection .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-N7123

Sulfacetamide 3 Publications Verification Sulphacetamide	Infection Classification of Application Fields Disease Research Fields	Environmental Pollutants Antibiotic Bacterial Fungal
Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections .

HY-121071

Ascamycin	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Nucleoside Antimetabolite/Analog Antibiotic
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against *Xanthomonas* species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for *Xanthomonas citri, Xanthomonas oryzae* and *Mycobacterium phlei*, respectively .

Cat. No.	상품명	Chemical Structure

HY-B0322S

Sulfamethoxazole-d4

1 Publications Verification

Sulfamethoxazole-d₄ (Ro 4-2130-d₄) is a deuterium labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .

HY-B0322S1

Sulfamethoxazole-13C6

Sulfamethoxazole- ¹³C₆ (Ro 4-2130- ¹³C₆) is a ¹³C labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .

HY-B0035S

Sulfamethazine-d4
Sulfamethazine-d₄ (Sulfadimidine-d₄) is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections) .

HY-B0273S

Sulfadiazine-d4
Sulfadiazine-d₄ is a deuterium labeled Sulfadiazine. Sulfadiazine is a sulfonamide antibiotic used for the treatment of toxoplasmosis .

HY-B0507S

Sulfathiazole-d4

Sulfathiazole-d₄ is a deuterium labeled Sulfathiazole. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish .

HY-B0688S2

Dapsone-13C12

Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B1267S1

Sulfaguanidine-13C6
Sulfaguanidine- ¹³C₆ is the ¹³C₆ labeled Sulfaguanidine. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.

HY-N7123S

Sulfacetamide-d4
Sulfacetamide-d₄ (Sulphacetamide-d₄) is the deuterium labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities .

HY-B0946S

Sulfamonomethoxine-d4
Sulfamonomethoxine-d₄ is a deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-B0688S

Dapsone-d8

Dapsone-d₈ is a deuterium labeled Dapsone. Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with antibacterial, antigenic and anti-inflammatory activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone can be used as an anticonvulsant and also in the research of skin and glioblastoma diseases .

HY-B0337S2

Sulfadimethoxine-13C6
Sulfadimethoxine- ¹³C₆ is the ¹³C-labeled Sulfadimethoxine. Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections .

HY-B0688S1

Dapsone-d4

Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B0273S1

Sulfadiazine-13C6
Sulfadiazine- ¹³C₆ is a labeled Sulfadiazine (HY-B0273). Sulfadiazine is a sulfonamide?antibiotic with antimalarial activity[1].

HY-135393S

Sulfadimethoxypyrimidine-d4
Sulfadimethoxypyrimidine-d₄ is a deuterium labeled Sulfadimethoxypyrimidine. Sulfadimethoxypyrimidine is a sulfonamide antibiotic with a broad-spectrum antibacterial effect .

HY-B0337S

Sulfadimethoxine-d4
Sulfadimethoxine-d₄ is a deuterium labeled Sulfadimethoxine (Sulphadimethoxine). Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections .

HY-B0337S1

Sulfadimethoxine-d6
Sulfadimethoxine-d₆ is the deuterium labeled Sulfadimethoxine. Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections .

HY-B1267S

Sulfaguanidine-d4
Sulfaguanidine-d₄ is the deuterium labeled Sulfaguanidine. Sulfaguanidine, belongs to the class of sulfonamide agent, is an orally active antibiotic. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery .

HY-N7123S1

Sulfacetamide-13C6
Sulfacetamide- ¹³C₆ (Sulphacetamide ¹³C₆) is the ¹³C₆ labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities .

HY-B0946S1

Sulfamonomethoxine-d3
Sulfamonomethoxine-d₃ is the deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-B0946S3

Sulfamonomethoxine-d3-1
Sulfamonomethoxine-d₃-1 is the deuterium labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-B0946S2

Sulfamonomethoxine-13C6
Sulfamonomethoxine- ¹³C₆ is the ¹³C₆ labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity .

HY-B0213S

Sulfameter-d4
Sulfameter-d₄ (Sulfametoxydiazine-d₄) is the deuterium labeled Sulfameter (HY-B0213) . Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections .

HY-W748688

N4-Acetylsulfamethoxazole-13C6
N4-Acetylsulfamethoxazole- ¹³C₆ (Acetylsulfamethoxazole- ¹³C₆) is the ¹³C-labeled N4-Acetylsulfamethoxazole (HY-W013266). N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is a metabolite of?Sulfamethoxazole (HY-B0322). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic, used for bacterial infections .

HY-B0213S1

Sulfameter-13C6
Sulfameter- ¹³C₆ (Sulfametoxydiazine- ¹³C₆) is the ¹³C₆ labeled Sulfameter (HY-B0213). Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections .

HY-B0688S3

Dapsone-15N2

Dapsone- ¹⁵N₂ (4,4′-Diaminodiphenyl sulfone- ¹⁵N₂) is ¹⁵N labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B1218S

Sulfaphenazole-d4

Sulfaphenazole-d₄ is the deuterium labeled Sulfaphenazole (HY-B1218). Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .

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