63-74-1
63-74-1
Chemical Structure
Sulfanilamide
Synonym(s): Sulphanilamide
- CAS No.: 63-74-1
- Formula:C6H8N2O2S
- Molecular Weight:172.21
IUPAC Name: 4-aminobenzenesulfonamide
InChIKey: FDDDEECHVMSUSB-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(N)C=C1)(N)=O
Biological Activity: ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum[1][2][3][4].
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Sulfanilamide | 99.90% | ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum. | ||||||||||||||||||||
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Sulfanilamide (Standard) | 99.83% | Sulfanilamide (Standard) is the analytical standard of Sulfanilamide. This product is intended for research and analytical applications. ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum. | ||||||||||||||||||||
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Sulfanilamide-d4 | 99.99% | Sulfanilamide-d4 is the deuterium labeled Sulfanilamide. Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM. | ||||||||||||||||||||
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References
- [1]. Liao X, et al. Antibiotic sulfanilamide biodegradation by acclimated microbial populations. Appl Microbiol Biotechnol. 2016 Mar;100(5):2439-47. [Content Brief]
- [2]. Padeĭskaia EN, et al. Sravnitel'naia aktivnost' depo-sul'fanilamidov pri éksperimental'noĭ infektsii mysheĭ, vyzvannoĭ K1. pneumoniae [Comparative activity of depot sulfanilamides in experimental infection in mice caused by K1. pneumoniae]. Antibiotiki. 1980 Mar;25(3):193-8. [Content Brief]
- [3]. T. MANN, et al. Sulphanilamide as a Specific Inhibitor of Carbonic Anhydrase. Nature, 1940, 146, 164-165.
- [4]. Findlay GM. The Action of Sulphanilamide on the Virus of Lymphogranuloma Venereum. Br J Exp Pathol. 1940 Dec;21(6):356–60.
