63-74-1
63-74-1
Chemical Structure
Sulfanilamide
Synonym(s): Sulphanilamide
- CAS No.: 63-74-1
- Formula:C6H8N2O2S
- Molecular Weight:172.21
IUPAC Name: 4-aminobenzenesulfonamide
InChIKey: FDDDEECHVMSUSB-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(N)C=C1)(N)=O
Biological Activity: ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sulfanilamide | 99.90% | ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum. | ||||||||||||||||||||
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Sulfanilamide (Standard) | 99.83% | Sulfanilamide (Standard) is the analytical standard of Sulfanilamide. This product is intended for research and analytical applications. ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum. | ||||||||||||||||||||
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Sulfanilamide-d4 | 99.99% | Sulfanilamide-d4 is the deuterium labeled Sulfanilamide. Sulfanilamide is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM. | ||||||||||||||||||||
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4-Azidobenzenesulfonamide | 4-Azidobenzenesulfonamide (Compound 12) is a precursor for the synthesis of 1,2,3-triazoles. | |||||||||||||||||||||
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p-Toluenesulfonamide | 99.98% | p-Toluenesulfonamide is a small-molecule anticancer agent and plasticizer. p-Toluenesulfonamide exerts antitumor activity by inducing lysosomal membrane permeabilization, cathepsin B release and lysosome-mediated cell death. p-Toluenesulfonamide modulates cholesterol distribution in lipid rafts of tumor cell membranes and the Akt/mTOR/p70S6K pathway. p-Toluenesulfonamide shows activity against various cancers including hepatocellular carcinoma, non-small cell lung cancer and tongue squamous cell carcinoma; intrapleural injection effectively reduces malignant pleural effusion without causing pleural adhesion. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum. p-Toluenesulfonamide can be used in cancer-related research. | ||||||||||||||||||||
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p-Toluenesulfonamide-15N | p-Toluenesulfonamide-15N is the 15N-labeled p-Toluenesulfonamide (HY-79602). p-Toluenesulfonamide is a small-molecule anticancer agent and plasticizer. p-Toluenesulfonamide exerts antitumor activity by inducing lysosomal membrane permeabilization, cathepsin B release and lysosome-mediated cell death. p-Toluenesulfonamide modulates cholesterol distribution in lipid rafts of tumor cell membranes and the Akt/mTOR/p70S6K pathway. p-Toluenesulfonamide shows activity against various cancers including hepatocellular carcinoma, non-small cell lung cancer and tongue squamous cell carcinoma; intrapleural injection effectively reduces malignant pleural effusion without causing pleural adhesion. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum. p-Toluenesulfonamide can be used in cancer-related research. | |||||||||||||||||||||
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p-Sulfamoylbenzaldehyde (Standard) | ≥98% | p-Sulfamoylbenzaldehyde (Standard) is the analytical standard of p-Sulfamoylbenzaldehyde. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Mafenide | 99.96% | Mafenide is a potent sulfonamide antimicrobial agent. Mafenide exhibits antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. Mafenide also exhibits antifungal activity against filamentous fungi (e.g., Lichtheimia and Aspergillus flavus). Mafenide can be used in the research of skin grafts on burn wounds, post-traumatic invasive fungal infections, and bacterially contaminated wounds. | ||||||||||||||||||||
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Mafenide hydrochloride (Standard) | ≥98% | Mafenide (hydrochloride) (Standard) is the analytical standard of Mafenide (hydrochloride). This product is intended for research and analytical applications. Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis. | ||||||||||||||||||||
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2-Aminobenzenesulfonamide | 99.90% | 2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor. | ||||||||||||||||||||
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4-Hydrazinylbenzenesulfonamide hydrochloride (Standard) | ≥98% | 4-Hydrazinylbenzenesulfonamide hydrochloride (Standard) is the analytical standard of 4-Hydrazinylbenzenesulfonamide hydrochloride. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Sodium Sulphanilate | 99.93% | Sodium Sulphanilate (Sodium 4-aminobenzenesulfonate) is a folic acid synthetase inhibitor and antifungal agent, as well as a structural analog of p-aminobenzoic acid, that competitively inhibits folate biosynthesis in fungal pathogens. Sodium Sulphanilate induces host disease resistance via changes in amino acid profiles, reduces chlorophyll content in peanut leaves at high concentrations, and controls rust diseases in various plant species. Sodium Sulphanilate is applicable to studies related to peanut rust. | ||||||||||||||||||||
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References
- [1]. Liao X, et al. Antibiotic sulfanilamide biodegradation by acclimated microbial populations. Appl Microbiol Biotechnol. 2016 Mar;100(5):2439-47. [Content Brief]
- [2]. Padeĭskaia EN, et al. Sravnitel'naia aktivnost' depo-sul'fanilamidov pri éksperimental'noĭ infektsii mysheĭ, vyzvannoĭ K1. pneumoniae [Comparative activity of depot sulfanilamides in experimental infection in mice caused by K1. pneumoniae]. Antibiotiki. 1980 Mar;25(3):193-8. [Content Brief]
- [3]. T. MANN, et al. Sulphanilamide as a Specific Inhibitor of Carbonic Anhydrase. Nature, 1940, 146, 164-165.
- [4]. Findlay GM. The Action of Sulphanilamide on the Virus of Lymphogranuloma Venereum. Br J Exp Pathol. 1940 Dec;21(6):356–60.
