321 Results for "

surface antigen

" in MedChemExpress (MCE) Product Catalog:
Products (321)

321 Results for "surface antigen" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-P99045
CAS No.: 1796566-95-4
Synonyms: HRS7; hRS7

Target:  

ADC Antibodies TROP2

Research Areas:  

Cancer

Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab can be used for the synthesis of antibody-drug conjugates (ADC) drug Sacituzumab govitecan (HY-132254). Sacituzumab govitecan can be used in the field of triple-negative breast cancer .
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4
4 Cited Publications
Cat. No.: HY-N0699
CAS No.: 2034-69-7
Synonyms: Dephnoretin; Thymelol
Daphnoretin (Dephnoretin; Thymelol) is a protein kinase C (PKC) activator that inhibits the expression of hepatitis B virus (HBV) surface antigen (HBsAg) and exhibits antiviral activity. Daphnoretin exerts its antitumor effects by inhibiting the activation of the PI3K/AKT signaling pathway and triggers the mitochondrial apoptosis pathway. Daphnoretin alleviates chondrocyte apoptosis and inflammatory responses by inhibiting endoplasmic reticulum stress and activation of the NLRP3 inflammasome. Daphnoretin regulates the differentiation and maturation of dendritic cells, inhibits their immunostimulatory function by downregulating the phosphorylation level of JNK, and thus exerts a protective effect in skin graft rejection .
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3
3 Cited Publications
Cat. No.: HY-P70154
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuEpithelial cell adhesion molecule/EpCAM, His; Epithelial Cell Adhesion Molecule; Ep-CAM; Adenocarcinoma-Associated antigen; Cell surface Glycoprotein Trop-1; Epithelial Cell surface antigen; Epithelial Glycoprotein; EGP; Epithelial Glycoprotein 314; EGP314; hEGP314; KSA; Tumor-Associated Calcium Signa
Species:  
Source:  
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2
2 Cited Publications
Cat. No.: HY-P99843
CAS No.: 2267989-53-5

Target:  

TROP2 ADC Antibodies

Research Areas:  

Cancer

Datopotamab is a humanized anti trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab can be used in the study of triple negative breast cancer and non-small cell lung cancer .
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2
2 Cited Publications
Cat. No.: HY-P99011
CAS No.: 1855925-27-7

Target:  

CD3

Research Areas:  

Cancer

Cibisatamab, a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab can be used for colorectal cancer research .
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2
2 Cited Publications
Cat. No.: HY-P86463
Synonyms: LHR antibody; BA-1 antibody; CD 44 antibody; CD44 antibody; CD44 antigen antibody; CD44 molecule; Indian blood group; antibody; CD44 molecule antibody; CD44_HUMAN antibody; CDw44 antibody; CDW44 antigen antibody; Cell surface glycoprotein CD44 antibody; chondroitin sulfate proteoglycan 8 antibody; CSPG8 antibody; ECMR-III antibody; Epican antibody; Extracellular matrix receptor III antibody; GP90 lymphocyte homing/adhesion receptor antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P74330
Purity:  ≥ 90%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: B-lymphocyte antigen CD19; CD19; B-lymphocyte surface antigen B4
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P72904
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD4
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P72720
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lymphocyte Function-Associated antigen 3; surface Glycoprotein LFA-3; CD58; LFA3; Ag3; CD58 antigen
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P72917
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Leukocyte surface antigen CD47; IAP; CD47; MER6
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-W854385A
Synonyms: SLeA sodium
Research Areas:  

Cancer

Sialyl Lewis A (SLeA) sodium is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A sodium promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A sodium shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A sodium can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
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1
1 Cited Publications
Cat. No.: HY-P80598
Synonyms: CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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1
1 Cited Publications
Cat. No.: HY-P7831
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rRhIntegrin-associated protein/CD47, Fc; Leukocyte surface antigen CD47; antigenic surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6
Source:  
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1
1 Cited Publications
Cat. No.: HY-P70486
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD28; CD28 antigen; CD28 molecule; T-cell-specific surface glycoprotein CD28; Tp44; TP44
Source:  
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1
1 Cited Publications
Cat. No.: HY-P80592
Synonyms: CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; CD11b; Leukocyte adhesion receptor MO1

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Mouse

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1
1 Cited Publications
Cat. No.: HY-P80608
Synonyms: CD81; TAPA1; TSPAN28; CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28; Tspan-28; CD81

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse

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1
1 Cited Publications
Cat. No.: HY-P80062
Synonyms: LHR antibody; BA-1 antibody; CD 44 antibody; CD44 antibody; CD44 antigen antibody; CD44 molecule (Indian blood group) antibody; CD44 molecule antibody; CD44_HUMAN antibody; CDw44 antibody; Cell surface glycoprotein CD44 antibody; chondroitin sulfate proteoglycan 8 antibody; CSPG8 antibody; ECMR-III antibody; Epican antibody; Extracellular matrix receptor III antibody; GP90 lymphocyte homing/adhesion receptor antibody; HCELL antibody; hematopoietic cell E- and L-selectin ligand antibody; Heparan sulfate proteoglycan antibody; Hermes antigen antibody; homing function and Indian blood group system antibody; HSA antibody; HUTCH-I antibody; HUTCH1 antibody; Hyaluronate receptor antibody; IN antibody; MC56 antibody; MDU2 antibody; MDU3 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, FC

Reactivity:  

Human, Mouse

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Cat. No.: HY-P99152
CAS No.: 140608-64-6
Synonyms: Muromanab-CD3

Research Areas:  

Inflammation/Immunology Cancer

Muromonab (Muromonab-CD3; OKT3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients .
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Cat. No.: HY-P99798
CAS No.: 2251756-52-0
Synonyms: AMG 420; BI-836909

Target:  

CD3

Research Areas:  

Cancer

Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines .
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Cat. No.: HY-147266
Purity:  95.83%
Synonyms: VIR-2218 sodium
Research Areas:  

Infection

Elebsiran (VIR-2218) sodium is a siRNA that targets and degrades hepatitis B virus (HBV) and hepatitis D virus (HDV) RNA transcripts. Elebsiran sodium leads to a significant decrease in HBV surface antigen (HBsAg) and a reduction in viral load. Elebsiran sodium binds to the sialic acid-depleted glycoprotein receptor (ASGPR) on the surface of liver cells through the GalNAc ligand, achieving liver-targeted delivery and demonstrating improved liver safety. Elebsiran sodium can be used for the study of chronic HBV/HDV infections .
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