18 Results for "

terminal deoxynucleotidyl transferase

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "terminal deoxynucleotidyl transferase" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-128744
CAS No.: 4408-78-0
Purity:  ≥98.0%
Phosphonoacetic acid is a potent antiviral agent. Phosphonoacetic acid inhibits a variety of herpesviruses, orthopoxviruses, and retroviruses. Phosphonoacetic acid strongly inhibits viral and cellular DNA polymerase, reverse transcriptase, and terminal deoxynucleotidyl transferase activities in a non-competitive or uncompetitive manner by binding to the pyrophosphate site of the enzyme. Phosphonoacetic acid is useful for research related to lymphoid leukemia, herpesvirus infection, and vaccinia virus skin lesions .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-D1668
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .
loading...
    loading...
Cat. No.: HY-158712
Purity:  ≥98.0%
3'-ONH2-dATP sodium solution (100mM) is a 3'-O-blocked reversible terminator deoxynucleotide triphosphate. 3'-ONH2-dATP sodium solution (100mM) stops DNA polymerization after single-nucleotide addition to an initiator strand, and its 3'-ONH2 blocking group can be removed to restore a free 3'-OH for subsequent extension .
loading...
    loading...
Cat. No.: HY-D1725
Cy3-dCTP is a directly fluorescently labeled deoxyribonucleotide, in which Cy3 is a cyanine fluorescent dye. Cy3-dCTP is used for direct enzymatic labeling of DNA and cDNA: with the aid of DNA polymerases, this modified nucleotide is incorporated into the extending DNA strand during processes such as reverse transcription, PCR, nick translation or random primer labeling .
loading...
    loading...
Cat. No.: HY-132142
CAS No.: 115899-39-3
Purity:  ≥98.0%
5-Propargylamino-dCTP is a sustrate for DNA polymerases. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis .
loading...
    loading...
Cat. No.: HY-150145
Cy5-UTP is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotidyl transferase (TdT). Cy5-UTP can be employed to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays that combine with Cy5-UTP .
loading...
    loading...
Cat. No.: HY-151651
CAS No.: 125607-09-2
Purity:  99.26%
Synonyms: Spacer Phosphoramidite 18
Target:  

Phosphoramidites

Research Areas:  

Others

Hexaethylene glycol phosphoramidite (Spacer Phosphoramidite 18) is an amide reagent used for oligonucleotide synthesis. Hexaethylene glycol phosphoramidite serves as a linker for the synthesis of nucleotide chains and qPCR probes .
loading...
    loading...
Cat. No.: HY-D1721
Research Areas:  

Others

Fluorescein-12-dATP is a fluorescein-labeled deoxyadenosine triphosphate and signal amplifier. Fluorescein-12-dATP can be incorporated into the 3'-end of exposed thrombin-binding aptamers via terminal deoxynucleotidyl transferase to form multi-labeled nucleic acid chains, which are used for signal amplification in thrombin detection. Fluorescein-12-dATP acts as a fluorescent detection probe in chip-based aptamer sandwich biosensors for the detection of thrombin in serum. Fluorescein-12-dATP can be used in studies related to thrombin detection .
loading...
    loading...
Cat. No.: HY-160841
CAS No.: 2567941-52-8
Research Areas:  

Others

Biotin-16-dCTP is a biotinylated deoxycytidine triphosphate that serves as an important DNA labeling substrate. Biotin-16-dCTP can be enzymatically incorporated into the 3' end of DNA probes via terminal deoxynucleotidyl transferase, forming a 1-3 nucleotide-long tail to achieve biotinylation of the probes. Biotin-16-dCTP enhances chemiluminescent detection of low-abundance targets such as specific tRNA isoacceptors through Northern blotting. Biotin-16-dCTP can also replace conventional dCTP to be integrated into single-stranded DNA generated by asymmetric polymerase chain reaction, which is applicable for bioconjugation or pull-down assays. Repeated freeze-thaw cycles of Biotin-16-dCTP should be avoided to prevent degradation of its function for probe biotinylation .
loading...
    loading...
Cat. No.: HY-174849
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

TdT-IN-1 (Compound 8c) is a selective and non-nucleoside terminal deoxynucleotidyl transferase (TdT) inhibitor with IC50 s of 0.11 and 0.19 μM for Mg 2+ and Mn 2+. TdT-IN-1 can be used for leukaemias and skin cancer research .
loading...
    loading...
Cat. No.: HY-128744R
CAS No.: 4408-78-0
Phosphonoacetic acid Standard is the analytical standard of Phosphonoacetic acid (HY-128744). This product is intended for research and analytical applications. Phosphonoacetic acid is a potent antiviral agent. Phosphonoacetic acid inhibits a variety of herpesviruses, orthopoxviruses, and retroviruses. Phosphonoacetic acid strongly inhibits viral and cellular DNA polymerase, reverse transcriptase, and terminal deoxynucleotidyl transferase activities in a non-competitive or uncompetitive manner by binding to the pyrophosphate site of the enzyme. Phosphonoacetic acid is useful for research related to lymphoid leukemia, herpesvirus infection, and vaccinia virus skin lesions .
loading...
    loading...
Cat. No.: HY-185452
CAS No.: 28070-54-4
Target:  

Drug Intermediate

Research Areas:  

Others

N4-Acetyldeoxycytidine triphosphate is a terminal deoxynucleotidyl transferase substrate. N4-Acetyldeoxycytidine triphosphate acts as a substrate for calf thymus terminal deoxynucleotidyl transferase and undergoes polymerization to form extended polydeoxynucleotide chains .
loading...
    loading...
Cat. No.: HY-119787
CAS No.: 27267-69-2
Synonyms: Collinomycin
α-Rubromycin (Collinomycin) is an antibiotic isolated from the mycelia of Streptomyces collinus. α-Rubromycin also acts as a DNA polymerase inhibitor, with an IC50 of 0.91 μM against bovine mammalian DNA polymerase. α-Rubromycin binds to the active region of DNA polymerase β, competes with nucleotide substrates for binding, and interferes with template-DNA interactions. α-Rubromycin inhibits the activities of telomerase, retroviral reverse transcriptase and terminal deoxynucleotidyl transferase, as well as the growth of Staphylococcus aureus. α-Rubromycin can be used in studies related to bacterial infections .
loading...
    loading...
Cat. No.: HY-KE8006

Terminal Deoxynucleotidyl Transferase (TdT) is a template-independent DNA polymerase that catalyzes the binding of deoxynucleotides to the 3' hydroxyl end of oligonucleotides, single-stranded DNA, or double-stranded DNA.

loading...
    loading...
Cat. No.: HY-128744A
CAS No.: 36983-81-0
Phosphonoacetic acid sodium is a potent antiviral agent. Phosphonoacetic acid sodium inhibits a variety of herpesviruses, orthopoxviruses, and retroviruses. Phosphonoacetic acid sodium strongly inhibits viral and cellular DNA polymerase, reverse transcriptase, and terminal deoxynucleotidyl transferase activities in a non-competitive or uncompetitive manner by binding to the pyrophosphate site of the enzyme. Phosphonoacetic acid sodium is useful for research related to lymphoid leukemia, herpesvirus infection, and vaccinia virus skin lesions .
loading...
    loading...
Cat. No.: HY-184852
CAS No.: 151-41-7
Synonyms: Dodecyl hydrogen sulphate; Dodecyl sulfate
Lauryl sulfate (Dodecyl hydrogen sulphate) is an anionic chaotropic surfactant. Lauryl sulfate dissolves viral envelopes, denatures viral proteins, inhibits viral infectivity and HIV-1 syncytium formation. Lauryl sulfate potently inhibits the infectivity of HSV-1 strain F (ED50 = 17.9 μM) and HSV-2 strain 333 (ED50 = 32.7 μM). Lauryl sulfate induces environmental toxicity, disrupting environmental balance and physiological processes of organisms. As a contaminant, Lauryl sulfate is toxic to aquatic and terrestrial organisms. Lauryl sulfate can be used in studies related to sexually transmitted infections .
loading...
    loading...
Cat. No.: HY-P71070
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DNTT; terminal transferase; DNA Nucleotidylexotransferase; Nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; TDT; terminal Deoxyribonucleotidyltransferase; terminal deoxynucleotidyltransferase; deoxynucleotidyltransferase, terminal; terminal Addi
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P81810
Synonyms: DNA nucleotidylexotransferase; DNTT; TDT; terminal addition enzyme; terminal deoxynucleotidyltransferase; terminal transferase

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

loading...
    loading...
  • 1