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Results for "

terminal deoxynucleotidyl transferase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA Stain (3) DNA/RNA Synthesis (3) Drug Intermediate (1) Fluorescent Dye (3) Nucleoside Antimetabolite/Analog (2) Reverse Transcriptase (1) Thrombin (1)
By Research Areas:	Cancer (2) Infection (1) Neurological Disease (1)
Click Chemistry:	Labeling and Fluorescence Imaging (3)
Oligonucleotides:	Nucleotide Analogs (1)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Kits MCE

Protéines recombinantes

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: JNK γ-Glutamyl Transferase (GGT) Farnesyl Transferase GGTase Glutathione S-transferase OGT NAMPT

Cat. No.	Nom du produit	Target	Áreas de investigación	Chemical Structure

HY-158712

3'-ONH2-dATP sodium solution (100 mM)	Nucleoside Antimetabolite/Analog	Others
3'-ONH2-dATP sodium solution (100mM) is a 3'-O-blocked reversible terminator deoxynucleotide triphosphate. 3'-ONH2-dATP sodium solution (100mM) stops DNA polymerization after single-nucleotide addition to an initiator strand, and its 3'-ONH2 blocking group can be removed to restore a free 3'-OH for subsequent extension .

HY-D1725

Cy3-dCTP	Fluorescent Dye DNA Stain	Others
Cy3-dCTP is a directly fluorescently labeled deoxyribonucleotide, in which Cy3 is a cyanine fluorescent dye. Cy3-dCTP is used for direct enzymatic labeling of DNA and cDNA: with the aid of DNA polymerases, this modified nucleotide is incorporated into the extending DNA strand during processes such as reverse transcription, PCR, nick translation or random primer labeling .

HY-D1668

Biotin-11-dCTP	DNA Stain Reverse Transcriptase	Infection Neurological Disease Cancer
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .

HY-132142

5-Propargylamino-dCTP	DNA/RNA Synthesis	Others
5-Propargylamino-dCTP is a sustrate for DNA polymerases. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-150145

Cy5-UTP	Nucleoside Antimetabolite/Analog Fluorescent Dye	Others
Cy5-UTP is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotidyl transferase (TdT). Cy5-UTP can be employed to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays that combine with Cy5-UTP .

HY-D1721

Fluorescein-12-dATP	Fluorescent Dye Thrombin	Others
Fluorescein-12-dATP is a fluorescein-labeled deoxyadenosine triphosphate and signal amplifier. Fluorescein-12-dATP can be incorporated into the 3'-end of exposed thrombin-binding aptamers via terminal deoxynucleotidyl transferase to form multi-labeled nucleic acid chains, which are used for signal amplification in thrombin detection. Fluorescein-12-dATP acts as a fluorescent detection probe in chip-based aptamer sandwich biosensors for the detection of thrombin in serum. Fluorescein-12-dATP can be used in studies related to thrombin detection .

HY-160841

Biotin-16-dCTP	DNA Stain DNA/RNA Synthesis	Others
Biotin-16-dCTP is a biotinylated deoxycytidine triphosphate that serves as an important DNA labeling substrate. Biotin-16-dCTP can be enzymatically incorporated into the 3' end of DNA probes via terminal deoxynucleotidyl transferase, forming a 1-3 nucleotide-long tail to achieve biotinylation of the probes. Biotin-16-dCTP enhances chemiluminescent detection of low-abundance targets such as specific tRNA isoacceptors through Northern blotting. Biotin-16-dCTP can also replace conventional dCTP to be integrated into single-stranded DNA generated by asymmetric polymerase chain reaction, which is applicable for bioconjugation or pull-down assays. Repeated freeze-thaw cycles of Biotin-16-dCTP should be avoided to prevent degradation of its function for probe biotinylation .

HY-174849

TdT-IN-1	DNA/RNA Synthesis	Cancer
TdT-IN-1 (Compound 8c) is a selective and non-nucleoside terminal deoxynucleotidyl transferase (TdT) inhibitor with IC₅₀s of 0.11 and 0.19 μM for Mg ²⁺ and Mn ²⁺. TdT-IN-1 can be used for leukaemias and skin cancer research .

HY-185452

N4-Acetyldeoxycytidine triphosphate	Drug Intermediate	Others
N4-Acetyldeoxycytidine triphosphate is a terminal deoxynucleotidyl transferase substrate. N4-Acetyldeoxycytidine triphosphate acts as a substrate for calf thymus terminal deoxynucleotidyl transferase and undergoes polymerization to form extended polydeoxynucleotide chains .

Cat. No.	Nom du produit	Type

HY-D1725

Cy3-dCTP	Fluorescent Dyes
Cy3-dCTP is a directly fluorescently labeled deoxyribonucleotide, in which Cy3 is a cyanine fluorescent dye. Cy3-dCTP is used for direct enzymatic labeling of DNA and cDNA: with the aid of DNA polymerases, this modified nucleotide is incorporated into the extending DNA strand during processes such as reverse transcription, PCR, nick translation or random primer labeling .

HY-D1668

Biotin-11-dCTP	Fluorescent Dyes
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .

Biotin-11-dCTP

Fluorescent Dyes

Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .

Cat. No.	Nom du produit	Type

HY-158712

3'-ONH2-dATP sodium solution (100 mM)	Biochemical Assay Reagents
3'-ONH2-dATP sodium solution (100mM) is a 3'-O-blocked reversible terminator deoxynucleotide triphosphate. 3'-ONH2-dATP sodium solution (100mM) stops DNA polymerization after single-nucleotide addition to an initiator strand, and its 3'-ONH2 blocking group can be removed to restore a free 3'-OH for subsequent extension .

HY-132142

5-Propargylamino-dCTP	Biochemical Assay Reagents
5-Propargylamino-dCTP is a sustrate for DNA polymerases. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-150145

Cy5-UTP	Biochemical Assay Reagents
Cy5-UTP is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotidyl transferase (TdT). Cy5-UTP can be employed to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays that combine with Cy5-UTP .

Cat. No.	Nom du produit

HY-KE8006

Terminal Deoxynucleotidyl Transferase (TdT)
Terminal Deoxynucleotidyl Transferase (TdT) is a template-independent DNA polymerase that catalyzes the binding of deoxynucleotides to the 3' hydroxyl end of oligonucleotides, single-stranded DNA, or double-stranded DNA.

Cat. No.	Compare	Nom du produit	Species	Source	Image

HY-P71070

	TDT Protein, Human (His) DNA nucleotidylexotransferase; terminal addition enzyme; terminal deoxynucleotidyltr; terminal deoxynucleotidyltransferase; terminal transferase; DNTT; TDT	Human	E. coli
	TDT protein, a template-independent DNA polymerase, non-specifically adds deoxynucleoside 5'-triphosphates to the 3'-end of a DNA initiator. It crucially contributes to in vivo processes, particularly adding nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during B- and T-cell maturation. TDT Protein, Human (His) is the recombinant human-derived TDT protein, expressed by E. coli , with N-6*His labeled tag.

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HY-P81810

	DNA Nucleotidylexotransferase Antibody (YA1555) DNA nucleotidylexotransferase; DNTT; TDT; terminal addition enzyme; terminal deoxynucleotidyltransferase; terminal transferase	WB	Human
	DNA Nucleotidylexotransferase Antibody (YA1555) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DNA Nucleotidylexotransferase.

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Cat. No.	Nom du produit		Classification

HY-D1725

Cy3-dCTP		Labeling and Fluorescence Imaging
Cy3-dCTP is a directly fluorescently labeled deoxyribonucleotide, in which Cy3 is a cyanine fluorescent dye. Cy3-dCTP is used for direct enzymatic labeling of DNA and cDNA: with the aid of DNA polymerases, this modified nucleotide is incorporated into the extending DNA strand during processes such as reverse transcription, PCR, nick translation or random primer labeling .

HY-D1668

Biotin-11-dCTP		Labeling and Fluorescence Imaging
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .

HY-D1721

Fluorescein-12-dATP		Labeling and Fluorescence Imaging
Fluorescein-12-dATP is a fluorescein-labeled deoxyadenosine triphosphate and signal amplifier. Fluorescein-12-dATP can be incorporated into the 3'-end of exposed thrombin-binding aptamers via terminal deoxynucleotidyl transferase to form multi-labeled nucleic acid chains, which are used for signal amplification in thrombin detection. Fluorescein-12-dATP acts as a fluorescent detection probe in chip-based aptamer sandwich biosensors for the detection of thrombin in serum. Fluorescein-12-dATP can be used in studies related to thrombin detection .

Cat. No.	Nom du produit		Classification

HY-132142

5-Propargylamino-dCTP		Nucleotide Analogs
5-Propargylamino-dCTP is a sustrate for DNA polymerases. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

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