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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
tobacco exposure biomarker
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "tobacco exposure biomarker" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: (-)-Cotinine; (S)-Cotinine; NIH-10498
Category:
Alkaloids Pyrrole Alkaloids Nicotiana tabacum L. Other Diseases Pyridine Alkaloids Plants Endogenous metabolite Disease Research Fields Solanaceae Extract
Target:
Category:
Alkaloids Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Synonyms: 2-Amino-α-carboline; AαC
Target:
Research Areas:
AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits .
Cat. No.: HY-W700491
CAS No.: 1189920-50-0
Synonyms: 2-Amino-α-carboline-15N3; AαC-15N3
Cat. No.: HY-113239S1
CAS No.: 159956-78-2
rel-Hydroxycotinine-d3 is the d3-labeled Hydroxycotinine (HY-113239). Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease .
Cat. No.: HY-113239S
CAS No.: 1311275-10-1
Hydroxycotinine-d3 is the d3-labeled Hydroxycotinine (HY-113239). Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease .
Cat. No.: HY-W653722
CAS No.: 71267-22-6
Synonyms: (S)-N-NAT; (S)-N'-Nitrosoanatabine
Target:
Research Areas:
(S) -N-Nitrosoanatabine ( (S) -N-NAT) is a potent carcinogen and biomarker of exposure to cigarette smoke. It′s found in a variety of tobacco products and oral snuff.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
