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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
vicinal
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "vicinal" in MCE Product Catalog:
1
1 Cited Publications
Research Areas:
DuP-697 is a member of the vicinal diaryl heterocycles and a potent, irreversible, selective and orally active COX-2 inhibitor (IC50 of 10 nM and 800 nM for human COX-2 and COX-1, respectively). DuP-697 exerts antiproliferative (IC50 of 42.8 nM), antiangiogenic and apoptotic effects on HT29 colorectal cancer cells. DuP-697 inhibits prostaglandin synthesis and has anti-inflammatory, anticancer and antipyretic effects .
Cat. No.: HY-W014815
CAS No.: 223463-14-7
Synonyms: 2-Bromopyridine-5-boronic acid
Target:
Research Areas:
BPBA (2-Bromopyridine-5-boronic acid) is a derivatization reagent derived from Boric acid (HY-Y0314) with enhanced ionization efficiency in positive-mode electrospray ionization mass spectrometry. BPBA forms boronate ester derivatives with vicinal diols. It enables rapid, catalyst-free labeling operations, improves the detection sensitivity of liquid chromatography/mass spectrometry, and reduces false positive errors .
Cat. No.: HY-75102
CAS No.: 14047-29-1
Cat. No.: HY-D1259
CAS No.: 2414276-32-5
Synonyms: VDP-green (NEP)
Cat. No.: HY-D1258
CAS No.: 2937705-58-1
Synonyms: VDP-green
Cat. No.: HY-177995
CAS No.: 142609-62-9
Synonyms: Monoisoamyl meso-2,3-dimercaptosuccinic acid
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Research Areas:
MiADMSA (Monoisoamyl meso-2,3-dimercaptosuccinic acid) is an orally active thiol chelator that can effectively remove heavy metals such as arsenic and lead from the body of animals. Arsenic binds with two vicinal sulfhydryl groups available in MiADMSA leading to marked reduction in body arsenic burden and also marked reduction in various oxidative stress parameters and antioxidant enzymes like-ROS, nitrite, TBARS, GSH, SOD and catalase. MiADMSA attenuates urinary bladder carcinogenesis, protects against oxidative stress, ameliorates copper-induced histopathology, reverses neurotoxicity, and is safe in animals. MiADMSA can be used in studies of bladder cancer, arsenic, and lead-induced developmental neurotoxicity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
