K-Ras G12C-IN-3
Based on 1 Customer Validation
K-Ras G12C-IN-3 (Compound VI-5) is an irreversible small molecule inhibitor of mutant K-Ras G12C. K-Ras G12C-IN-3 can be used in the research of cancers.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 1629268-19-4
- Formula: C21H19Cl3N2O3
- Molecular Weight:453.75
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 1629268-19-4
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Appearance Solid
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Molecular Weight 453.75
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Formula C21H19Cl3N2O3
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Color White to off-white
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SMILES
ClC(C=C(OC)C(C(N1CCN(C(C=C)=O)CC1)=O)=C2)=C2C3=CC(Cl)=CC=C3Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : ≥ 30 mg/mL (66.12 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2039 mL | 11.0193 mL | 22.0386 mL | 55.0964 mL |
| 5 mM | 0.4408 mL | 2.2039 mL | 4.4077 mL | 11.0193 mL | |
| 10 mM | 0.2204 mL | 1.1019 mL | 2.2039 mL | 5.5096 mL | |
| 15 mM | 0.1469 mL | 0.7346 mL | 1.4692 mL | 3.6731 mL | |
| 20 mM | 0.1102 mL | 0.5510 mL | 1.1019 mL | 2.7548 mL | |
| 25 mM | 0.0882 mL | 0.4408 mL | 0.8815 mL | 2.2039 mL | |
| 30 mM | 0.0735 mL | 0.3673 mL | 0.7346 mL | 1.8365 mL | |
| 40 mM | 0.0551 mL | 0.2755 mL | 0.5510 mL | 1.3774 mL | |
| 50 mM | 0.0441 mL | 0.2204 mL | 0.4408 mL | 1.1019 mL | |
| 60 mM | 0.0367 mL | 0.1837 mL | 0.3673 mL | 0.9183 mL |
K-Ras G12C-IN-3 Related Classifications
HY-18606 Related Classifications
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