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  4. Shishijimicin C

Shishijimicin C is a novel antitumor agent found from the Ascidian Didemnum proliferum. Shishijimicin C shows anti-tumor activity with highly potent cytotoxicities. Shishijimicin C is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

Shishijimicin C Chemical Structure

Shishijimicin C Chemical Structure

CAS No. : 503860-52-4

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Description

Shishijimicin C is a novel antitumor agent found from the Ascidian Didemnum proliferum. Shishijimicin C shows anti-tumor activity with highly potent cytotoxicities[1]. Shishijimicin C is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

In Vitro

Shishijimicin C (compound 3) (1.7-6.3 pg/mL) shows high cytotoxicity for 3Y1, Hela and P388 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: 3Y1, Hela and P388 cells
Concentration: 1.7-6.3 pg/mL
Incubation Time:
Result: Showed IC50 values of 4.8, 6.3, and 1.7 pg/mL for 3Y1, Hela and P388 cells, respectively.
Molecular Weight

967.16

Formula

C45H50N4O12S4

CAS No.
SMILES

O=C(C1=C(NC2=CC=C3O)C(C2=C3)=CC=N1)[C@@]([C@@H]([C@H]4O[C@H](OC[C@@H]5NCC)C[C@@H]5OC)O)([C@H](O[C@H]4O[C@@H](C#C/C=C\C#C[C@@]6(C7)O)C(/C6=C\CSSSC)=C(C7=O)NC(OC)=O)C)SC

Structure Classification
Initial Source

Didemnum proliferum

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Shishijimicin C
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HY-N10539
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