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Cat. No.: HY-107414R

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SKA-121 (Standard)

SKA-121 (Standard) is the analytical standard of SKA-121 (HY-107414). This product is intended for research and analytical applications. SKA-121 is a selective KCa3.1 activator. SKA-121 exhibits EC₅₀s of 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively.

For research use only. We do not sell to patients.

CAS No.: 1820708-73-3
Formula: C₁₂H₁₀N₂O
Molecular Weight:198.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

SKA-121 (Standard) Chemical Structure

CAS No.: 1820708-73-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

EC50: 109 nM (K_Ca3.1), 4.4 μM (K_Ca2.3)^[1]

Chemical Information

CAS No. 1820708-73-3
Molecular Weight 198.22
Formula C₁₂H₁₀N₂O
SMILES

NC1=NC2=CC(C)=C3C=CC=CC3=C2O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Coleman N, et al. New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1. Mol Pharmacol. 2014 Sep;86(3):342-57. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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