2. Neuronal Signaling
  3. Monoamine Oxidase
  4. SL-25.1188

SL-25.1188 is a potent monoamine oxidase B (MAO-B) inhibitor with Ki values of 2.9 and 8.5 nM for human MAO-B and rat MAO-B, respectively. SL-25.1188 can be used for positron emission tomography.

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SL-25.1188 Chemical Structure

SL-25.1188 Chemical Structure

CAS No. : 185835-97-6

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Description

SL-25.1188 is a potent monoamine oxidase B (MAO-B) inhibitor with Ki values of 2.9 and 8.5 nM for human MAO-B and rat MAO-B, respectively. SL-25.1188 can be used for positron emission tomography[1].

IC50 & Target[1]

hMAO-B

2.9 nM (Ki)

rMAO-B

8.5 nM (Ki)

Molecular Weight

374.31

Formula

C16H17F3N2O5
CAS No.
SMILES

O=C1O[C@@H](CN1C2=NOC3=C2C=CC(OCCCC(F)(F)F)=C3)COC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SL-25.1188 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SL-25.1188185835-97-6Monoamine OxidaseMAOInhibitorinhibitorinhibit

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