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Cat. No.: HY-132129

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SOS1-IN-2

SOS1-IN-2 (Compound 1-1) is an inhibitor of SOS1 with an IC₅₀ value of 5 nM. SOS1-IN-2 can be used in tumor research.

For research use only. We do not sell to patients.

CAS No.: 2359690-13-2
Formula: C₂₂H₂₃F₃N₄O
Molecular Weight:416.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

SOS1-IN-2 Chemical Structure

CAS No.: 2359690-13-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

SOS1-IN-2 (Compound 1-1) is an inhibitor of SOS1 with an IC₅₀ value of 5 nM. SOS1-IN-2 can be used in tumor research^[1].

All Ras Isoforms :

Chemical Information

CAS No. 2359690-13-2
Molecular Weight 416.44
Formula C₂₂H₂₃F₃N₄O
SMILES

O=C1C=C2N=C(C)N=C(N[C@@H](C3=CC=CC(C(F)(F)F)=C3C)C)C2=CN1C4(C)CC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Juergen Ramharter, et al. Novel benzylamino substituted pyridopyrimidinones and derivatives as sos1 inhibitors. Patent, WO2019122129, 2019-06-27.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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SOS1-IN-2

All Ras Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

SOS1-IN-2 Related Classifications

HY-132129 Related Classifications