SR-32685
SR-32685 is a NAMPT activator and neuroprotective agent. SR-32685 enhances the enzymatic activity of hNAMPT, prevents intracellular NAD depletion, and protects neurons from death induced by toxic misfolded prion proteins. SR-32685 can be used in the research of protein misfolding neurodegenerative diseases and metabolic diseases.
For research use only. We do not sell to patients.
- CAS No.: 2791469-14-0
- Formula: C22H24N6O2S
- Molecular Weight:436.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SR-32685 protects neuronal cells against TPrP-induced death with an EC50 of 40 nM[1].
SR-32685 (1 μM) increases the activity of h-NAMPT by at least 10% at a concentration of 1 μM[1].
SR-32685 exhibits a stability of more than 15 min in h-microsome (liver)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2791469-14-0
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Molecular Weight 436.53
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Formula C22H24N6O2S
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SMILES
O=C(C(C=NN12)=C2NC(C3=CC=C(OCC)C=C3)=CC1=S)NCCCN4C=CN=C4C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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