Vesleteplirsen sodium
Vesleteplirsen sodium (SRP-5051 sodium) is a peptide-conjugated morpholino oligonucleotide (PPMO) that mediates exon jumping molecular effects. Vesleteplirsen sodium targets exon 51 of the DMD gene pre-mRNA, remodeling the transcript splicing process, restoring the protein translation read frame, and generating internally truncated pseudodystrophy proteins. Vesleteplirsen sodium can be used for research related to Duchenne muscular dystrophy.
For research use only. We do not sell to patients.
- Formula: C404H616N202Na30O130P30
- Molecular Weight:11342 (free acid)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Molecular Weight 11342 (free acid)
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Formula C404H616N202Na30O130P30
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SMILES
[Vesleteplirsen (sodium)]
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Synonyms
SRP-5051 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)