Stachybotramide
Stachybotramide is a natural fungal metabolite with the property of modulating the activity of cholesteryl ester transfer protein (CETP). Stachybotramide stimulates the transfer of cholesteryl esters (CE) from high-density lipoprotein (HDL) to very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), increasing the transfer efficiency by 1.3- to 1.5-fold. Stachybotramide slightly reduced the transfer of cholesteryl esters from LDL and VLDL to HDL at 0.5 mM. The effect of Stachybotramide on the transfer of triglycerides (TG) from HDL was not significant. By these results, Stachybotramide was shown to preferentially stimulate the CETP-mediated transfer of cholesteryl esters from HDL to VLDL and LDL.
For research use only. We do not sell to patients.
- CAS No.: 149598-71-0
- Formula: C25H35NO5
- Molecular Weight:429.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 149598-71-0
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Molecular Weight 429.55
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Formula C25H35NO5
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SMILES
C[C@@]([C@@](C(C)1C)([H])CC2)(CC[C@H]1O)[C@@]3([C@@H]2C)OC4=C(CN5CCO)C(C5=O)=CC(O)=C4C3
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Structure Classification
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Initial Source
Stachybotrys cylindrospora
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Stachybotramide Related Classifications
HY-N8353 Related Classifications
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