Substance P(1-4)
Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation.
For research use only. We do not sell to patients.
- CAS No.: 57468-16-3
- Formula: C22H40N8O5
- Molecular Weight:496.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Substance P(1-4) (0.1 nM-1 μM) inhibits endogenous erythroid colony (EEC) formation in PV bone marrow cultures[1].
Substance P(1-4) (0.1 nM-1 μM; CD36+/GpA- cells) decreases of erythroid colony numbers of 47% and inhibits proliferation of PV CD36+/GpA- cells of 30 %[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:PV CD36+/GpA- cells
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Concentration:0.1 nM-1 μM
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Incubation Time:2 days
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Result:Inhibited proliferation of PV CD36+/GpA- cells of 30 %.
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Cell Line:PV CD36+/GpA- cells
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Concentration:10 nM
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Incubation Time:2 days
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Result:Increased the percentage of cell death of 27.3%.
Chemical Information
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CAS No. 57468-16-3
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Molecular Weight 496.60
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Formula C22H40N8O5
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Sequence Shortening
RPKP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Substance P(1-4) Related Classifications
HY-P3598 Related Classifications
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