Suzetrigine N-oxide
Based on 1 Customer Validation
Suzetrigine N-oxide (the third compound in P57) is a derivative of Suzetrigine (HY-148800). Suzetrigine N-oxide is an inhibitor of voltage-gated sodium channels (Nav1.8) and can be used for research on the treatment of pain, especially neuropathic pain.
For research use only. We do not sell to patients.
- Purity: 99.05%
- CAS No.: 2649467-76-3
- Formula: C21H20F5N3O5
- Molecular Weight:489.39
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
Nav1.8 |
Chemical Information
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CAS No. 2649467-76-3
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Appearance Solid
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Molecular Weight 489.39
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Formula C21H20F5N3O5
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Color White to off-white
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SMILES
NC(C1=CC(NC([C@H]2[C@H](C3=C(C(F)=C(C=C3)F)OC)[C@@H]([C@@](C)(O2)C(F)(F)F)C)=O)=CC=[N+]1[O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (102.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0434 mL | 10.2168 mL | 20.4336 mL | 51.0840 mL |
| 5 mM | 0.4087 mL | 2.0434 mL | 4.0867 mL | 10.2168 mL | |
| 10 mM | 0.2043 mL | 1.0217 mL | 2.0434 mL | 5.1084 mL | |
| 15 mM | 0.1362 mL | 0.6811 mL | 1.3622 mL | 3.4056 mL | |
| 20 mM | 0.1022 mL | 0.5108 mL | 1.0217 mL | 2.5542 mL | |
| 25 mM | 0.0817 mL | 0.4087 mL | 0.8173 mL | 2.0434 mL | |
| 30 mM | 0.0681 mL | 0.3406 mL | 0.6811 mL | 1.7028 mL | |
| 40 mM | 0.0511 mL | 0.2554 mL | 0.5108 mL | 1.2771 mL | |
| 50 mM | 0.0409 mL | 0.2043 mL | 0.4087 mL | 1.0217 mL | |
| 60 mM | 0.0341 mL | 0.1703 mL | 0.3406 mL | 0.8514 mL | |
| 80 mM | 0.0255 mL | 0.1277 mL | 0.2554 mL | 0.6386 mL | |
| 100 mM | 0.0204 mL | 0.1022 mL | 0.2043 mL | 0.5108 mL |
Suzetrigine N-oxide Related Classifications
HY-182195 Related Classifications
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