1. Protein Tyrosine Kinase/RTK
  2. Syk
  3. Syk-IN-1

Syk-IN-1 

Cat. No.: HY-12657 Purity: 99.18% ee.: 100.00%
Handling Instructions

Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM.

For research use only. We do not sell to patients.

Syk-IN-1 Chemical Structure

Syk-IN-1 Chemical Structure

CAS No. : 1491150-77-6

Size Stock
5 mg Check price and availability
10 mg Check price and availability
25 mg Check price and availability
50 mg Check price and availability

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM[1].

Molecular Weight

366.42

Formula

C₁₈H₂₂N₈O

CAS No.

1491150-77-6

SMILES

NC(C1=NN=C(N[[email protected]@H]2CCCC[[email protected]@H]2N)N=C1NC3=CC=CC4=C3NC=C4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (272.91 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7291 mL 13.6455 mL 27.2911 mL
5 mM 0.5458 mL 2.7291 mL 5.4582 mL
10 mM 0.2729 mL 1.3646 mL 2.7291 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5 mg/mL (13.65 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Syk-IN-1SykSpleen tyrosine kinaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Syk-IN-1
Cat. No.:
HY-12657
Quantity:
MCE Japan Authorized Agent: