1. MAPK/ERK Pathway
  2. MAP3K
  3. TAK1-IN-2

TAK1-IN-2 

Cat. No.: HY-132172
Handling Instructions

TAK1-IN-2 is a potent and selective TAK1 inhibitor, with an IC50> of 2 nM.

For research use only. We do not sell to patients.

TAK1-IN-2 Chemical Structure

TAK1-IN-2 Chemical Structure

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Description

TAK1-IN-2 is a potent and selective TAK1 inhibitor, with an IC50> of 2 nM[1].

IC50 & Target[1]

TAK1

2 nM (IC50)

In Vitro

TAK1-IN-2 (compound 54) (10 μM) has no effect on cell viability in TNF-α stimulated HCT-15 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

540.52

Formula

C₂₆H₂₆F₂N₆O₅

SMILES

O=C(C1=CC2=C(CN(C(C3=NC(C(N(CC4=CC=CC=C4OC(F)F)[[email protected]](C)C(NC)=O)=O)=CN3)=O)C2)C=C1)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

TAK1-IN-2MAP3KMAP kinase kinase kinase, MEKK, MAPKKKTAK1Inhibitorinhibitorinhibit

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TAK1-IN-2
Cat. No.:
HY-132172
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