2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Taplucainium chloride

Taplucainium chloride is a Sodium Channel blocker. Taplucainium chloride exhibits 70-95% inhibition at 10μM. Taplucainium chloride can be used as an analgesic agent.

For research use only. We do not sell to patients.

Taplucainium chloride Chemical Structure

Taplucainium chloride Chemical Structure

CAS No. : 2489565-37-7

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Description

Taplucainium chloride is a Sodium Channel blocker. Taplucainium chloride exhibits 70-95% inhibition at 10μM. Taplucainium chloride can be used as an analgesic agent[1][2].

Molecular Weight

386.96

Formula

C23H31ClN2O
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C[N+]1(CCCCCC1)CC2=CC=CC=C2)NC3=C(C)C=CC=C3C.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (25.84 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5842 mL 12.9212 mL 25.8425 mL
5 mM 0.5168 mL 2.5842 mL 5.1685 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5842 mL 12.9212 mL 25.8425 mL 64.6062 mL
5 mM 0.5168 mL 2.5842 mL 5.1685 mL 12.9212 mL
10 mM 0.2584 mL 1.2921 mL 2.5842 mL 6.4606 mL
15 mM 0.1723 mL 0.8614 mL 1.7228 mL 4.3071 mL
20 mM 0.1292 mL 0.6461 mL 1.2921 mL 3.2303 mL
25 mM 0.1034 mL 0.5168 mL 1.0337 mL 2.5842 mL
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Taplucainium chloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Taplucainium2489565-37-7Sodium ChannelNa channelsNa+ channelsInhibitorinhibitorinhibit

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