TCO-PEG3-acid
Based on 1 Customer Validation
TCO-PEG3-acid is a click chemistry reagent that contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
For research use only. We do not sell to patients.
- Purity: 96.01%
- CAS No.: 2141981-86-2
- Formula: C18H31NO7
- Molecular Weight:373.44
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
TCO-PEG3-acid is a click chemistry PEG linker with a terminal carboxylic acid group. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators to form a stable amide bond[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2141981-86-2
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Appearance Viscous Liquid
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Molecular Weight 373.44
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Formula C18H31NO7
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Color Colorless to light yellow
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SMILES
O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCC(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (669.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6778 mL | 13.3890 mL | 26.7781 mL | 66.9452 mL |
| 5 mM | 0.5356 mL | 2.6778 mL | 5.3556 mL | 13.3890 mL | |
| 10 mM | 0.2678 mL | 1.3389 mL | 2.6778 mL | 6.6945 mL | |
| 15 mM | 0.1785 mL | 0.8926 mL | 1.7852 mL | 4.4630 mL | |
| 20 mM | 0.1339 mL | 0.6695 mL | 1.3389 mL | 3.3473 mL | |
| 25 mM | 0.1071 mL | 0.5356 mL | 1.0711 mL | 2.6778 mL | |
| 30 mM | 0.0893 mL | 0.4463 mL | 0.8926 mL | 2.2315 mL | |
| 40 mM | 0.0669 mL | 0.3347 mL | 0.6695 mL | 1.6736 mL | |
| 50 mM | 0.0536 mL | 0.2678 mL | 0.5356 mL | 1.3389 mL | |
| 60 mM | 0.0446 mL | 0.2232 mL | 0.4463 mL | 1.1158 mL | |
| 80 mM | 0.0335 mL | 0.1674 mL | 0.3347 mL | 0.8368 mL | |
| 100 mM | 0.0268 mL | 0.1339 mL | 0.2678 mL | 0.6695 mL |