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Cat. No.: HY-184102

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Tedixaban

Name: Tedixaban
Brand: MedChemExpress
SKU: HY-184102
Availability: PreOrder

(Synonyms: Tedixabanum)

Tedixaban (Tedixabanum) is a Factor Xa inhibitor and anticoagulant with an IC₅₀ of 0.50 nM. Tedixaban is applicable to research on thrombosis-related complications.

For research use only. We do not sell to patients.

CAS No.: 1333126-80-9
Formula: C₂₃H₂₂ClN₅O₂
Molecular Weight:435.91

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tedixaban Chemical Structure

CAS No.: 1333126-80-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

Tedixaban (Tedixabanum) is a Factor Xa inhibitor and anticoagulant with an IC₅₀ of 0.50 nM. Tedixaban is applicable to research on thrombosis-related complications.

In Vitro

Cardiovascular Regulation

Tedixaban (DD217) is a small-molecule compound belonging to the class of coagulation factor Xa inhibitors. It has an in vitro IC₅₀ of 0.50 nM, exhibits tight-binding characteristics, and acts as a competitive binding ligand, with an MM/GBSA total binding free energy of -46.9 kcal/mol^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1333126-80-9
Molecular Weight 435.91
Formula C₂₃H₂₂ClN₅O₂
SMILES

O=C(C1=CC=C(N(C)C(C)=N)C=C1)NC2=CC=C(C)C=C2C(NC3=NC=C(C=C3)Cl)=O
Synonyms

Tedixabanum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Shulga DA, et al. Investigation of the tight binding mechanism of a new anticoagulant DD217 to factor Xa by means of molecular docking and molecular dynamics. Journal of biomolecular structure & dynamics. 2023 Jul;41(10):4723-4734. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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