Thalidomide-5-O-C12-NH2 hydrochloride

Cat. No.: HY-149569 Purity: 99.90%: FAQs
Data Sheet SDS COA Handling Instructions

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Thalidomide-5-O-C12-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C12-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs.

For research use only. We do not sell to patients.

Thalidomide-5-O-C12-NH2 hydrochloride Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 375	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 600	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1200	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1920	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Description	Thalidomide-5-O-C12-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-O-C12-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs^[1].
Molecular Weight	494.02
Formula	C₂₅H₃₆ClN₃O₅
Appearance	Solid
Color	White to off-white
SMILES	O=C1C(C=CC(OCCCCCCCCCCCCN)=C2)=C2C(N1C(CC3)C(NC3=O)=O)=O.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Purity & Documentation	Purity: 99.90% Select Batch: Data Sheet (238 KB) SDS (251 KB) COA (244 KB) HNMR (231 KB) LCMS (102 KB) Handling Instructions (2659 KB)

Thalidomide-5-O-C12-NH2 hydrochloride Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-5-O-C12-NH2Ligands for E3 LigaseE3 ligase-recruiting MoietyMolecular gelcereblon ligandPROTACCRBN proteintarget protein ligandconjugateInhibitorinhibitorinhibit

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