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Cat. No.: HY-45808

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Thalidomide-azetidine-CHO

Thalidomide-azetidine-CHO is a synthesized Ligands for E3 Ligase that incorporates the Thalidomide (HY-14658) based cereblon ligand used in PROTAC technology.

For research use only. We do not sell to patients.

CAS No.: 2416132-70-0
Formula: C₁₇H₁₅N₃O₅
Molecular Weight:341.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Thalidomide-azetidine-CHO Chemical Structure

CAS No.: 2416132-70-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Thalidomide-azetidine-CHO is a synthesized Ligands for E3 Ligase that incorporates the Thalidomide (HY-14658) based cereblon ligand used in PROTAC technology^[1].

IC₅₀ & Target

Cereblon

All Ligands for E3 Ligase Isoforms :

Chemical Information

CAS No. 2416132-70-0
Molecular Weight 341.32
Formula C₁₇H₁₅N₃O₅
SMILES

O=C1N(C2CCC(NC2=O)=O)C(C3=CC=C(N4CC(C=O)C4)C=C31)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wuhan Humanwell Innovative Drug Research and Development Center Limited Company; Humanwell Healthcare (Group) Co., Ltd. Preparation of imidazopyridine compounds as IRAK4 degraders. China, CN117777126 A 2024-03-29

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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