2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. Tilsotolimod sodium

Tilsotolimod (IMO-2125) sodium is a TLR9 agonist. Tilsotolimod sodium activates the TLR9 signaling pathway, triggers downstream pro-inflammatory and immunostimulatory pathways, enhances the uptake and killing of cancer cells, and induces adaptive immune responses. Tilsotolimod sodium is applicable to research related to melanoma and colorectal cancer.

For research use only. We do not sell to patients.

DNA, d(P-thio)(T-C-c7G-A-A-C-c7G-T-T-C-c7G), 3′,3′′′-[O,O′-(2-hydroxy-1,3-propanediyl) bis(hydrogen phosphorothioate)], sodium salt (1:22)

Tilsotolimod sodium Chemical Structure

CAS No. : 2089768-67-0

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Tilsotolimod sodium Related Antibodies

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Description

Tilsotolimod (IMO-2125) sodium is a TLR9 agonist. Tilsotolimod sodium activates the TLR9 signaling pathway, triggers downstream pro-inflammatory and immunostimulatory pathways, enhances the uptake and killing of cancer cells, and induces adaptive immune responses. Tilsotolimod sodium is applicable to research related to melanoma and colorectal cancer[1].

In Vitro

Tilsotolimod sodium exerts anti-tumor activity either alone or in combination with Ipilimumab (HY-P9901) and/or Nivolumab (HY-P9903)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tilsotolimod sodium Related Antibodies
Molecular Weight

7228 (free acid)

Formula

C223H262N74Na22O115P22S22
CAS No.
SMILES

[Tilsotolimod (sodium)]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tilsotolimod sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tilsotolimod2089768-67-0IMO-2125IMO2125IMO 2125Toll-like Receptor (TLR)Inhibitorinhibitorinhibit

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