country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-111483A

Copy Link Print Information

Tizaterkib hexanedioic acid

Name: Tizaterkib hexanedioic acid
Brand: MedChemExpress
SKU: HY-111483A
Availability: PreOrder

3 Cited Publications

Avis client

Based on 3 publication(s) in Google Scholar

Tizaterkib hexanedioic acid (example 18) is a potent and selective ERK2 inhibitor, with an IC₅₀ of 0.6 nM.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2097416-93-6
Formule: C₂₄H₂₄F₂N₈O₂.1/2C₆H₁₀O₄
Masse moléculaire:567.57

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Tizaterkib hexanedioic acid Chemical Structure

CAS No.: 2097416-93-6

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Publications (3)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Tizaterkib hexanedioic acid (example 18) is a potent and selective ERK2 inhibitor, with an IC₅₀ of 0.6 nM^[1].

IC₅₀ & Target

^[1]

ERK2

0.6 nM (IC₅₀)

Voir tous les produits spécifiques à Isoform ERK :

Chemical Information

CAS No. 2097416-93-6
Masse moléculaire 567.57
Formule C₂₄H₂₄F₂N₈O₂.1/2C₆H₁₀O₄
SMILES

OC(CCCCC(O)=O)=O.O=C1C2=NC(C3=NC(NC4=CC=NN4C)=NC=C3C)=CN2C[C@@H](N1CC5=CC(F)=C(C=C5)F)COC.[1/2]
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

All

Sort by:

Journal Impact Factor

Int J Mol Sci

ERK1/2 Inhibition via the Oral Administration of Tizaterkib Alleviates Noise-Induced Hearing Loss While Tempering down the Immune Response. [Abstract]

2024 Jun 7;25(12):6305. PMID: 38928015
Vet Microbiol

Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) induces IL-6 production through TAK-1/JNK/AP-1 and TAK-1/NF-κB signaling pathways. [Abstract]

2021 May:256:109061. PMID: 33836390
bioRxiv

ERK1/2 Inhibition Alleviates Noise-Induced Hearing Loss While Tempering Down the Immune Response. [Abstract]

2023 Oct 20:2023.10.18.563007. PMID: 37905140

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. WARD, Richard, Andrew, et al. DIHYDROIMIDAZOPYRAZINONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER. WO2017080979A1.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Tizaterkib hexanedioic acid

3 Cited Publications

100 mg Obtenir un devis

Subscribe to the

MedChemExpress

Newsletter

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis

Amount: USD 0.00

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Publications (3)
Pureté et documentation
Références

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

Nom du produit:
CAS No.:
Species:
Pureté:
Quantité:

Tizaterkib hexanedioic acid

Publications Citing Use of MedChemExpress (MCE) Tizaterkib hexanedioic acid

Voir tous les produits spécifiques à Isoform ERK