TLR2 antagonist-3
TLR2 antagonist-3 is a Toll-like receptor 2 (TLR2) antagonist with an IC50 of 13.32 μM. TLR2 antagonist-3 exhibits predicted metabolic stability and is applicable to the research of inflammatory and immune-related diseases.
For research use only. We do not sell to patients.
- CAS No.: 380160-63-4
- Formula: C24H22N2O4
- Molecular Weight:402.44
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
In Vitro
TLR2 antagonist-3 (Compound T9) exhibits a high predicted human intestinal absorption rate, a low risk of CYP2D6 inhibition, and a plasma clearance rate of 4.755 mL/min/kg, indicating favorable druglike properties[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
-
CAS No. 380160-63-4
-
Molecular Weight 402.44
-
Formula C24H22N2O4
-
SMILES
O=C(OCC(NC1=CC(C(C)=O)=CC=C1)=O)C2=C(CCCC3)C3=NC4=CC=CC=C42
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLR2 antagonist-3 Related Classifications
HY-184714 Related Classifications
Powered by Bioz