TLR7/8 agonist 11
TLR7/8 agonist 11 (compound 30) is a potent agonist of hTLR7 and hTLR8, with EC50s of 31.1 nM and 13.1 nM, respectively. TLR7/8 agonist 11 plays an important role in adaptive and innate immune responses.
For research use only. We do not sell to patients.
- Formula: C28H38N8O2
- Molecular Weight:518.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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human TLR7 31.1 nM (EC50) |
TLR8 13.1 nM (EC50) |
Chemical Information
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Molecular Weight 518.65
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Formula C28H38N8O2
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SMILES
NC1=NC2=CN(N=C2C(N[C@H](CO)CCC)=N1)CC3=CC=C(C=C3OC)CN(C(CC4=CC=CN=C4)C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)