TM11
Based on 1 Customer Validation
TM11, a Tanshinone mimic, is a potent HuR inhibitor that can inhibit HuR-RNA complex formation. TM11 reduces LPS-induced inflammatory response in murine macrophages.
For research use only. We do not sell to patients.
- Purity: 97.49%
- Formula: C18H11NO5S
- Molecular Weight:353.35
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Storage:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 353.35
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Formula C18H11NO5S
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Color Dark purple to black
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SMILES
O=C1C2=C(N(S(=O)(C3=CC=CC=C3)=O)C=C2C4=CC=CO4)C=CC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (141.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8301 mL | 14.1503 mL | 28.3006 mL | 70.7514 mL |
| 5 mM | 0.5660 mL | 2.8301 mL | 5.6601 mL | 14.1503 mL | |
| 10 mM | 0.2830 mL | 1.4150 mL | 2.8301 mL | 7.0751 mL | |
| 15 mM | 0.1887 mL | 0.9434 mL | 1.8867 mL | 4.7168 mL | |
| 20 mM | 0.1415 mL | 0.7075 mL | 1.4150 mL | 3.5376 mL | |
| 25 mM | 0.1132 mL | 0.5660 mL | 1.1320 mL | 2.8301 mL | |
| 30 mM | 0.0943 mL | 0.4717 mL | 0.9434 mL | 2.3584 mL | |
| 40 mM | 0.0708 mL | 0.3538 mL | 0.7075 mL | 1.7688 mL | |
| 50 mM | 0.0566 mL | 0.2830 mL | 0.5660 mL | 1.4150 mL | |
| 60 mM | 0.0472 mL | 0.2358 mL | 0.4717 mL | 1.1792 mL | |
| 80 mM | 0.0354 mL | 0.1769 mL | 0.3538 mL | 0.8844 mL | |
| 100 mM | 0.0283 mL | 0.1415 mL | 0.2830 mL | 0.7075 mL |