Tolazoline (Standard)
Tolazoline (Standard) is the analytical standard of Tolazoline. This product is intended for research and analytical applications. Tolazoline (Imidaline) is an α-adrenergic receptor antagonist. Tolazoline inhibits Noradrenaline (HY-13715)-induced cell contraction, modulates vascular resistance, increases arterial pressure, and reverses bradycardia and tachypnea. Tolazoline can be used to study erectile dysfunction, α2-adrenergic receptor agonist-related poisoning, and skin vascular disease research.
For research use only. We do not sell to patients.
- CAS No.: 59-98-3
- Formula: C10H12N2
- Molecular Weight:160.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 59-98-3
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Molecular Weight 160.22
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Formula C10H12N2
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SMILES
C1(CC2=CC=CC=C2)=NCCN1
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Synonyms
Imidaline (Standard); NSC35110 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Megens AA, et al. Further validation of in vivo and in vitro pharmacological procedures for assessing the alpha 2/alpha 1-selectivity of test compounds: (1). Alpha-adrenoceptor antagonists. Eur J Pharmacol. 1986 Sep 23;129(1-2):49-55. [Content Brief]
[2]. Schwartz DD, et al. Selectivity of atipamezole, yohimbine and tolazoline for alpha-2 adrenergic receptor subtypes: implications for clinical reversal of alpha-2 adrenergic receptor mediated sedation in sheep. J Vet Pharmacol Ther. 1998 Oct;21(5):342-7. [Content Brief]
[3]. Costa P, et al. Adrenergic receptors on smooth muscle cells isolated from human penile corpus cavernosum. J Urol. 1993 Sep;150(3):859-63. [Content Brief]
[4]. Rogers RA, et al. Pharmacologic modulation of the cutaneous vasculature in the isolated perfused porcine skin flap. J Pharm Sci. 1994 Dec;83(12):1682-9. [Content Brief]
[5]. Lei L, et al. Activation of L-type calcium channel by tolazoline derivatives: role of isothiocyanate moiety. J Cardiovasc Pharmacol. 1998 May;31(5):721-33. [Content Brief]
[6]. BENFEY BG, et al. VASOCONSTRICTOR ACTION OF TOLAZOLINE. Br J Pharmacol Chemother. 1964 Feb;22(1):66-71. [Content Brief]
[7]. Hsu WH, et al. Effects of tolazoline and yohimbine on xylazine-induced central nervous system depression, bradycardia, and tachypnea in sheep. J Am Vet Med Assoc. 1987 Feb 15;190(4):423-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tolazoline (Standard) Related Classifications
HY-A0066R Related Classifications
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