TCF19 - transcription factor 19 Gene

Also Known as SC1; TCF-19

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6941

About TCF19

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,158,589-31,164,215 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele and 189 orthologues. Ubiquitous expression in lymph node (RPKM 8.0), appendix (RPKM 5.7) and 25 other tissues.

Summary

This gene encodes a protein that contains a PHD-type zinc finger domain and likely functions as a transcription factor. The encoded protein plays a role proliferation and Apoptosis of pancreatic beta cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

TCF19 Products (3)

mRNA Protein Name
NM_001077511.2 NP_001070979.1 transcription factor 19
NM_001318908.2 NP_001305837.1 transcription factor 19
NM_007109.3 NP_009040.2 transcription factor 19

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21516116 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TCF19 Protein Structure

FHA

FHA: FHA domain (36 - 105)

PHD

PHD: PHD-finger (296 - 341)

  • 0
  • 100
  • 200
  • 300
  • 345 a.a.
Protein Preferred Names Protein Names

transcription factor 19

  • transcription factor SC1

TCF19 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TCF19 Q9Y242 ZGPAT Homo sapiens Q8N5A5-2
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 ZGPAT Homo sapiens Q8N5A5-2
Y2H Array
32296183
Intra
TCF19 Q9Y242 NFKBID Homo sapiens Q8NI38
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 NFKBID Homo sapiens Q8NI38
Y2H Array
32296183
Intra
TCF19 Q9Y242 NOXA1 Homo sapiens Q86UR1-2
Y2H Array
32296183
Intra
TCF19 Q9Y242 NOXA1 Homo sapiens Q86UR1-2
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 RHOH Homo sapiens Q15669
Y2H Array
32296183
Intra
TCF19 Q9Y242 RHOH Homo sapiens Q15669
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 ZNF474 Homo sapiens Q6S9Z5
Y2H Array
32296183
Intra
TCF19 Q9Y242 ZNF474 Homo sapiens Q6S9Z5
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
Intra
TCF19 Q9Y242 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 PDLIM7 Homo sapiens Q9NR12
Y2H Array
32296183
Intra
TCF19 Q9Y242 PDLIM7 Homo sapiens Q9NR12
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 PFDN5 Homo sapiens Q99471
Y2H Array
32296183
Intra
TCF19 Q9Y242 PFDN5 Homo sapiens Q99471
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 TRIB3 Homo sapiens Q96RU7
Y2H Array
32296183
Intra
TCF19 Q9Y242 TRIB3 Homo sapiens Q96RU7
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
TCF19 Q9Y242 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra
TCF19 Q9Y242 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra
TCF19 Q9Y242 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 CEP76 Homo sapiens Q8TAP6
Y2H Prey Pooling
32296183
Intra
TCF19 Q9Y242 CEP76 Homo sapiens Q8TAP6
Y2H Array
32296183
Intra
TCF19 Q9Y242 E2F6 Homo sapiens O75461
Anti Tag CoIP
28514442
Intra
TCF19 Q9Y242 E2F6 Homo sapiens O75461
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Psoriasis 8

  • PSORS8

  • Psoriasis Susceptibility 8

  • Psoriasis 8, Susceptibility To
Psoriasis 9

  • PSORS9

  • Psoriasis 9, Susceptibility To

  • Psoriasis Susceptibility 9
Psoriasis 7

  • PSORS7

  • Psoriasis 7, Susceptibility To

  • Psoriasis Susceptibility 7

  • Psoriasis

  • Psoriasis Vulgaris

  • Pv
Peeling Skin Syndrome

  • Deciduous Skin

  • Familial Continuous Skin Peeling Syndrome

  • Idiopathic Deciduous Skin

  • Keratosis Exfoliativa Congenita

  • Pss

  • Peeling Skin Disease

  • Skin Peeling Syndrome

  • Familial Continuous Skin Peeling

  • Keratolysis Exfoliativa Congenita

  • Exfoliation Syndrome

  • Keratolysis Exfoliativa
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14301 TCF19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22849 Tcf19 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29363 Tcf19 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TCF19 RGD RGD:1302974
Macaca mulatta TCF19 VGNC VGNC:83493
Felis catus TCF19 VGNC VGNC:66022
Canis familiaris TCF19 VGNC VGNC:47191
Bos taurus TCF19 VGNC VGNC:35688
Mus musculus TCF19 MGD MGI:103180
Others TCF19 NCBI