1. GPCR/G Protein
  2. Protease-Activated Receptor (PAR)
  3. UDM-001651

UDM-001651 

Cat. No.: HY-128345
Handling Instructions

UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM). UDM-001651 shows antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP).

For research use only. We do not sell to patients.

UDM-001651 Chemical Structure

UDM-001651 Chemical Structure

CAS No. : 1477497-01-0

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Description

UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM). UDM-001651 shows antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP)[1].

IC50 & Target

IC50: 4 nM (PAR4)[1]
Kd: 1.4 nM (PAR4)[1]

Molecular Weight

513.56

Formula

C₂₈H₂₃N₃O₅S

CAS No.

1477497-01-0

SMILES

COC1=CC(OCC2=CC=CC(OCC3=CC=CC=C3)=C2)=C4C=C(C5=CN6C(SC(OC)=N6)=N5)OC4=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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UDM-001651
Cat. No.:
HY-128345
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