UGM-IN-2
UGM-IN-2 is a UGM inhibitor with a Kd of 20 μM. It binds to the UGM isoforms of K. pneumoniae (Klebsiella pneumoniae) and M. tuberculosis (Mycobacterium tuberculosis) and inhibits mycobacterial growth. UGM-IN-2 can be used in studies related to mycobacterial infections and tuberculosis.
For research use only. We do not sell to patients.
- CAS No.: 1027102-49-3
- Formula: C18H13Cl2IN2O2S
- Molecular Weight:519.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
UGM-IN-2 (the penultimate compound in Supplementary Document S12) is a UGM inhibitor. UGM, a flavin-dependent enzyme unique to microorganisms, catalyzes the ring isomerization of UDP‑Galp to UDP‑Galf. As a key enzyme in furanose galactose synthesis, it represents a potential target for anti-infective therapy[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1027102-49-3
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Molecular Weight 519.18
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Formula C18H13Cl2IN2O2S
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SMILES
O=C(O)C(NC1=NC(=CS1)C=2C=CC(Cl)=CC2Cl)CC3=CC=C(I)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UGM-IN-2 Related Classifications
HY-113652 Related Classifications
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