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Cat. No.: HY-117722

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JW 618

Name: JW 618
Brand: MedChemExpress
SKU: HY-117722
Price: 130.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

JW 618 is a selective ABHD6 inhibitor, with IC₅₀s of 38 and 13 nM for mouse and rat ABHD6.
The product specifications provided below refer solely to the active content of JW 618.

For research use only. We do not sell to patients.

Purity : 99.9%
CAS No.: 1416133-88-4
Formula: C₁₇H₁₄F₆N₂O₂
Molecular Weight:392.30

Storage:

Solution, -20°C, 2 years

JW 618 Chemical Structure

CAS No.: 1416133-88-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

JW 618 is a selective ABHD6 inhibitor, with IC₅₀s of 38 and 13 nM for mouse and rat ABHD6^[1].
The product specifications provided below refer solely to the active content of JW 618.

In Vitro

JW 618 (0.1-50 μM, 30 min) inhibits protein expression of MAGL and ABHD6 in mouse or rat brain proteomes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1416133-88-4
Appearance Liquid
Molecular Weight 392.30
Formula C₁₇H₁₄F₆N₂O₂
SMILES

O=C(N(CC1=CC(C2=CC=NC=C2)=CC=C1)C)OC(C(F)(F)F)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chang JW, et al. Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chem Biol. 2012 May 25;19(5):579-88. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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