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Cat. No.: HY-168126

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VEGFR-2-IN-56

VEGFR-2-IN-56 (compund 12e) is a potent VEGFR-2 inhibitor (IC₅₀=45.9 nM).

For research use only. We do not sell to patients.

Formula: C₂₂H₂₂BrN₅O₄
Molecular Weight:500.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

VEGFR-2-IN-56 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

VEGFR-2-IN-56 (compund 12e) is a potent VEGFR-2 inhibitor (IC₅₀=45.9 nM)^[1].

IC₅₀ & Target

VEGFR-2^[1]

All VEGFR Isoforms :

Chemical Information

Molecular Weight 500.35
Formula C₂₂H₂₂BrN₅O₄
SMILES

O=C(N1CCC(C(N/N=C2C(NC3=C\2C=C(Br)C=C3)=O)=O)CC1)NC4=CC=C(OC)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eldehna WM, et al. Design, synthesis, and in silico insights of novel N'-(2-oxoindolin-3-ylidene)piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors. Bioorg Chem. 2024 Dec;153:107829. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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VEGFR-2-IN-56

All VEGFR Isoforms