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Cat. No.: HY-178968

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VEGFR-2-IN-76

VEGFR-2-IN-76 (Compound GL-3) is a potent VEGFR-2 inhibitor with an IC₅₀ value of 5.44 μM. VEGFR-2-IN-76 can be used for cancer research.

For research use only. We do not sell to patients.

Formula: C₁₉H₂₉N₅O₂
Molecular Weight:359.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

VEGFR-2-IN-76 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

VEGFR-2-IN-76 (Compound GL-3) is a potent VEGFR-2 inhibitor with an IC₅₀ value of 5.44 μM. VEGFR-2-IN-76 can be used for cancer research^[1].

IC₅₀ & Target^[1]

VEGFR-2

5.44 μM (IC₅₀)

All VEGFR Isoforms :

Chemical Information

Molecular Weight 359.47
Formula C₁₉H₂₉N₅O₂
SMILES

CCN(CCC(NCC(C)(NC(C1=C2C=CC=CC2=NN1)=O)C)=O)CC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gu X, et al. Discovery of novel VEGFR-2 inhibitors through virtual screening, synthesis and bioactivity evaluation. Bioorg Med Chem Lett. 2025 Oct 3:130423. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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VEGFR-2-IN-76

All VEGFR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

VEGFR-2-IN-76 Related Classifications

HY-178968 Related Classifications