VEGFR2-IN-4
VEGFR2-IN-4 (compound 25) is a potent and selective VEGFR2 kinase inhibitor, with a GI50 of 0.7 nM. VEGFR2-IN-4 shows anti-angiogenic effect. VEGFR2-IN-4 can be used for the research of rheumatoid arthritis.
For research use only. We do not sell to patients.
- CAS No.: 3049398-38-8
- Formula: C23H20N4O3S
- Molecular Weight:432.49
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All VEGFR Isoforms
More
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | GI50 |
>10000 nM
Compound: 25
|
Growth inhibition of mouse BaF3 cells incubated for 72 hrs by CCK-8 assay
Growth inhibition of mouse BaF3 cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 37216810] |
| BaF3 | GI50 |
0.7 nM
Compound: 25
|
Growth inhibition of mouse BaF3 cells harboring TEL-VEGFR2 incubated for 72 hrs by CCK-8 assay
Growth inhibition of mouse BaF3 cells harboring TEL-VEGFR2 incubated for 72 hrs by CCK-8 assay
|
[PMID: 37216810] |
Chemical Information
-
CAS No. 3049398-38-8
-
Molecular Weight 432.49
-
Formula C23H20N4O3S
-
SMILES
O=C(C1=CC(OC)=CC=C1)NC2=CC(SC3=CC=C4C(NN=C4NC(C)=O)=C3)=CC=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz