Violaxanthin (HPLC≥90%)
Violaxanthin (HPLC≥90%) is a naturally derived diepoxy xanthophyll carotenoid and light-harvesting accessory pigment with biological activities such as antioxidation and anti-inflammation. Violaxanthin (HPLC≥90%) transfers excitation energy to chlorophyll a under low-light conditions. Violaxanthin (HPLC≥90%) participates in the xanthophyll cycle and dissipates excess light energy in the form of heat, thereby protecting thylakoid membrane lipids from photo-oxidative damage. Violaxanthin (HPLC≥90%) exhibits activities including inhibition of lipid peroxidation, quenching of singlet oxygen, scavenging of DPPH free radicals, and scavenging of ABTS+ free radicals. Violaxanthin (HPLC≥90%) can be used in antioxidant-related research.
For research use only. We do not sell to patients.
- CAS No.: 126-29-4
- Formula: C40H56O4
- Molecular Weight:600.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
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Biological Activity
Violaxanthin (HPLC≥90%) is converted into antheraxanthin and zeaxanthin in the leaves of wild-type Arabidopsis thaliana under high light conditions, while this conversion does not occur in the leaves of the npq1-2 mutant (lacking functional violaxanthin de-epoxidase); instead, it accumulates in the form of a violaxanthin+antheraxanthin+zeaxanthin pool in the leaves of the Arabidopsis thaliana npq1-2 mutant, and this accumulation occurs under both low light and high light conditions[1].
Violaxanthin (HPLC≥90%) (1,500 µmol of photons·m-2·s-1; 15 min) converts into antheraxanthin and zeaxanthin under high light, and this process occurs in leaves of the Arabidopsis npq4-1 mutant; by contrast, no such conversion is observed in leaves of the npq4-1 npq1-2 double mutant, which lacks functional violaxanthin de-epoxidase[1].
Violaxanthin (HPLC≥90%) can be heterologously synthesized in Saccharomyces cerevisiae by reconstructing a β-carotene synthesis pathway synergistically enhanced by truncated ZEP, crtZ and Arabidopsis redox chaperones, with a corresponding yield of 7.3 mg/g cell dry weight. Targeting ZEP to the endoplasmic reticulum via the Cpr5p signal peptide can further increase violaxanthin yield, and the maximum violaxanthin yield of the cCrZEPer engineered strain in Saccharomyces cerevisiae strain YPH500 reaches 31 μg/g cell dry weight[2].
Violaxanthin (HPLC≥90%) is biosynthesized by zeaxanthin (HY-120318) in photosynthetic eukaryotes (including higher plants) through anther xanthin under the action of zeaxanthin cyclooxygenase (ZEP), and participates in the lutein cycle to eliminate excess light energy[2].
Violaxanthin (HPLC≥90%) (1.25-80 µg/mL) exhibits concentration-dependent reducing capacity and DPPH free radical scavenging activity in vitro, with an EC50 of 41.42 µg/mL[3].
Violaxanthin (HPLC≥90%) (1.25-80 µg/mL) exhibits potent, concentration-dependent ABTS+ free radical scavenging activity in vitro, with an EC50 value of 15.25 µg/mL[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 126-29-4
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Molecular Weight 600.87
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Formula C40H56O4
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SMILES
C[C@@](O1)(C[C@H](CC2(C)C)O)[C@@]12/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/[C@]34[C@](O3)(C[C@H](CC4(C)C)O)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Violaxanthin (HPLC≥90%) Related Classifications
HY-N9625A Related Classifications
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