WAY-385995
Based on 1 Customer Validation
WAY-385995 is an active molecule for the study of amyloid diseases and synucleinopathies.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 97.0%
- CAS No.: 6484-31-7
- 화학식: C13H11N5
- 분자량:237.26
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- Protocol
- 순도&문서
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Help & FAQs
Biological Activity
제품 설명
Chemical Information
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CAS No. 6484-31-7
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Appearance Solid
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분자량 237.26
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화학식 C13H11N5
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Color White to light yellow
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SMILES
N/N=C(C1=C(N2)C=CC=C1)\N=C2C3=CC=NC=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
DMSO : 33.33 mg/mL (140.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocol
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Amyloid: Congo Red Amyloid Staining
Congo red amyloid staining is a histochemical method used to detect extracellular amyloid deposits in tissue sections based on the affinity of Congo red dye for β-pleated sheet-rich protein aggregates. When bound to amyloid, Congo red produces characteristic apple-green birefringence under polarized light microscopy, which is widely regarded as a diagnostic feature of amyloid deposition in histopathology. The diagnostic principle relies on the combination of dye binding (congophilia) and optical anisotropy under polarized illumination, which distinguishes amyloid from most non-amyloid eosinophilic extracellular deposits in routine histological evaluation. Amyloid identification by Congo red staining remains a cornerstone in diagnostic pathology despite the availability of adjunct methods such as immunohistochemistry and mass spectrometry, particularly because of its ability to localize deposits directly within tissue architecture. The specificity of Congo red-positive deposits is incre
순도&문서
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Data Sheet (245 KB)
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SDS (581 KB)
- English - EN (581 KB)
- Français - FR (581 KB)
- Deutsch - DE (581 KB)
- Norwegian - NO (581 KB)
- Español - ES (581 KB)
- Swedish - SV (581 KB)
- Italian - IT (581 KB)
- Korean - KR (581 KB)
- Portuguese - PT (581 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2148 mL | 21.0739 mL | 42.1479 mL | 105.3696 mL |
| 5 mM | 0.8430 mL | 4.2148 mL | 8.4296 mL | 21.0739 mL | |
| 10 mM | 0.4215 mL | 2.1074 mL | 4.2148 mL | 10.5370 mL | |
| 15 mM | 0.2810 mL | 1.4049 mL | 2.8099 mL | 7.0246 mL | |
| 20 mM | 0.2107 mL | 1.0537 mL | 2.1074 mL | 5.2685 mL | |
| 25 mM | 0.1686 mL | 0.8430 mL | 1.6859 mL | 4.2148 mL | |
| 30 mM | 0.1405 mL | 0.7025 mL | 1.4049 mL | 3.5123 mL | |
| 40 mM | 0.1054 mL | 0.5268 mL | 1.0537 mL | 2.6342 mL | |
| 50 mM | 0.0843 mL | 0.4215 mL | 0.8430 mL | 2.1074 mL | |
| 60 mM | 0.0702 mL | 0.3512 mL | 0.7025 mL | 1.7562 mL | |
| 80 mM | 0.0527 mL | 0.2634 mL | 0.5268 mL | 1.3171 mL | |
| 100 mM | 0.0421 mL | 0.2107 mL | 0.4215 mL | 1.0537 mL |
WAY-385995 Related Classifications
HY-49450 Related Classifications
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