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Cat. No.: HY-186320

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Xanomeline-NH-Boc

Xanomeline-NH-Boc is a derivative of Xanomeline (HY-105182), which serves as the orthosteric pharmacophore of M1/M4 muscarinic agonist 4 (HY-187957) for activating mAChR1/4.

For research use only. We do not sell to patients.

CAS No.: 1018846-42-8
Formula: C₁₉H₃₂N₄O₃S
Molecular Weight:396.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Xanomeline-NH-Boc Chemical Structure

CAS No.: 1018846-42-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

Xanomeline-NH-Boc is a derivative of Xanomeline (HY-105182), which serves as the orthosteric pharmacophore of M1/M4 muscarinic agonist 4 (HY-187957) for activating mAChR1/4^[1].

IC₅₀ & Target

^[1]

mAChR1

mAChR4

All mAChR Isoforms :

In Vitro

Xanomeline-NH-Boc (compound 22) serves as an intermediate in the synthesis of the M1/M4 muscarinic agonist 4 (HY-187957) (compound 26b), and acts as its orthosteric pharmacophore for activating mAChR1/4^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1018846-42-8
Molecular Weight 396.55
Formula C₁₉H₃₂N₄O₃S
SMILES

CN1CC(C2=NSN=C2OCCCCCCNC(OC(C)(C)C)=O)=CCC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Su Y, et al. The Design, Synthesis and Pharmacological Characterization of Potent Xanomeline-Based M1 and M4 mAChR Bitopic Ligands. Journal of medicinal chemistry. 2026 Aug 13;69(15):18530-18552.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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