2. Anti-infection Apoptosis
  3. Fungal Apoptosis
  4. Xanthochymol

Xanthochymol is an antifungal agent found in Clusia rosea. Xanthochymol can induce fungal apoptosis.

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Xanthochymol

Xanthochymol Chemical Structure

CAS No. : 52617-32-0

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Xanthochymol Related Antibodies

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Description

Xanthochymol is an antifungal agent found in Clusia rosea. Xanthochymol can induce fungal apoptosis[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
4 μg/mL
Compound: 7
Cytotoxicity against human A549 cells after 3 days by SRB assay
Cytotoxicity against human A549 cells after 3 days by SRB assay
[PMID: 20232858]
DU-145 IC50
4 μg/mL
Compound: 7
Cytotoxicity against human DU145 cells after 3 days by SRB assay
Cytotoxicity against human DU145 cells after 3 days by SRB assay
[PMID: 20232858]
KB IC50
4.6 μg/mL
Compound: 7
Cytotoxicity against human vincristine-resistant KB cells overexpressing p-glycoprotein after 3 days by SRB assay
Cytotoxicity against human vincristine-resistant KB cells overexpressing p-glycoprotein after 3 days by SRB assay
[PMID: 20232858]
KB IC50
5 μg/mL
Compound: 7
Cytotoxicity against human KB cells after 3 days by SRB assay
Cytotoxicity against human KB cells after 3 days by SRB assay
[PMID: 20232858]
LNCaP ED50
8 μM
Compound: 14
Growth inhibition of human LNCAP cells xenografted in ip dosed NCr nu/nu mouse administered once daily from day 3 to 6 after implantation measured on day 7 by MTT-based hollow-fiber test
Growth inhibition of human LNCAP cells xenografted in ip dosed NCr nu/nu mouse administered once daily from day 3 to 6 after implantation measured on day 7 by MTT-based hollow-fiber test
[PMID: 19161316]
SW480 IC50
8.3 μM
Compound: 4
Cytotoxicity against human SW480 cells after 72 hrs by MTT assay
Cytotoxicity against human SW480 cells after 72 hrs by MTT assay
[PMID: 15787435]
U-251 IC50
2.3 μM
Compound: 6
Cytotoxicity against human U251MG cells assessed as reduction in cell viability after 72 hrs by CyQuant dye-based assay
Cytotoxicity against human U251MG cells assessed as reduction in cell viability after 72 hrs by CyQuant dye-based assay
[PMID: 28729053]
Molecular Weight

602.80

Formula

C38H50O6
CAS No.
SMILES

CC(CC[C@@H](C(C)=C)C[C@@]12C([C@@](C(C(C(C3=CC(O)=C(C=C3)O)=O)=C1O)=O)(C(C)([C@H](C2)C/C=C(C)\C)C)C/C=C(C)\C)=O)=C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Xanthochymol Related Classifications

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Xanthochymol52617-32-0FungalApoptosisapoptosisinfectionInhibitorinhibitorinhibit

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