1. Anti-infection
  2. Virus Protease
  3. ZIKV-IN-5

ZIKV-IN-5 

Cat. No.: HY-151448
Handling Instructions

ZIKV-IN-5 (compound 5c) is a low-cytotoxicity and acid-stable anti-ZIKV agent (EC50=0.71 μM). ZIKV-IN-5 effectively inhibits the activity of ZIKV NS5 MTase.

For research use only. We do not sell to patients.

ZIKV-IN-5 Chemical Structure

ZIKV-IN-5 Chemical Structure

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Description

ZIKV-IN-5 (compound 5c) is a low-cytotoxicity and acid-stable anti-ZIKV agent (EC50=0.71 μM). ZIKV-IN-5 effectively inhibits the activity of ZIKV NS5 MTase[1].

IC50 & Target

EC50:0.71 μM (ZIKV)[1].

In Vitro

ZIKV-IN-5 (0-200 μM; 96 h) shows low cytotoxicity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: Vero cells
Concentration: 0-200 μM
Incubation Time: 96 h
Result: Exhibited low cytotoxicities with a CC50 value of more than 200 μM
Molecular Weight

583.83

Formula

C36H45NO4Si

SMILES

O=C1OCC=C1/C=C/[[email protected]@H]2C(CC[[email protected]]3([H])[[email protected]](C)(CO[Si](C4=CC=CC=C4)(C(C)(C)C)C5=CC=CC=C5)/C(CC[[email protected]@]23C)=N/O)=C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
ZIKV-IN-5
Cat. No.:
HY-151448
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