β-Pompilidotoxin
β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells.
For research use only. We do not sell to patients.
- CAS No.: 216064-36-7
- Formula: C71H124N22O17
- Molecular Weight:1557.88
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
β-Pompilidotoxin (β-PMTX) increases resurgent current in wild-type neurons and induced resurgent current in med neurons. β-Pompilidotoxin (10 μM) modestly but significantly increased the decay time constant (τdecay) of currents evoked by a step from -90 to 0 mV from 0.52 to 0.73 msec in wild-type Purkinje cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 216064-36-7
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Appearance Solid
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Molecular Weight 1557.88
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Formula C71H124N22O17
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Color White to off-white
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Synonyms
β-PMTX
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Sequence
Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu-NH2
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Sequence Shortening
RIKIGLFDQLSRL-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : ≥ 100 mg/mL (64.19 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.6419 mL | 3.2095 mL | 6.4190 mL | 16.0474 mL |
| 5 mM | 0.1284 mL | 0.6419 mL | 1.2838 mL | 3.2095 mL | |
| 10 mM | 0.0642 mL | 0.3209 mL | 0.6419 mL | 1.6047 mL | |
| 15 mM | 0.0428 mL | 0.2140 mL | 0.4279 mL | 1.0698 mL | |
| 20 mM | 0.0321 mL | 0.1605 mL | 0.3209 mL | 0.8024 mL | |
| 25 mM | 0.0257 mL | 0.1284 mL | 0.2568 mL | 0.6419 mL | |
| 30 mM | 0.0214 mL | 0.1070 mL | 0.2140 mL | 0.5349 mL | |
| 40 mM | 0.0160 mL | 0.0802 mL | 0.1605 mL | 0.4012 mL | |
| 50 mM | 0.0128 mL | 0.0642 mL | 0.1284 mL | 0.3209 mL | |
| 60 mM | 0.0107 mL | 0.0535 mL | 0.1070 mL | 0.2675 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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