β-Pompilidotoxin
β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 216064-36-7
- 分子式: C71H124N22O17
- 分子量:1557.88
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保管条件:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
製品説明
体外実験
β-Pompilidotoxin (β-PMTX) increases resurgent current in wild-type neurons and induced resurgent current in med neurons. β-Pompilidotoxin (10 μM) modestly but significantly increased the decay time constant (τdecay) of currents evoked by a step from -90 to 0 mV from 0.52 to 0.73 msec in wild-type Purkinje cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 216064-36-7
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性状 Solid
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分子量 1557.88
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分子式 C71H124N22O17
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Color White to off-white
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別名
β-PMTX
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配列
Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu-NH2
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シーケンスの短縮
RIKIGLFDQLSRL-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外:
H2O : ≥ 100 mg/mL (64.19 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
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- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.6419 mL | 3.2095 mL | 6.4190 mL | 16.0474 mL |
| 5 mM | 0.1284 mL | 0.6419 mL | 1.2838 mL | 3.2095 mL | |
| 10 mM | 0.0642 mL | 0.3209 mL | 0.6419 mL | 1.6047 mL | |
| 15 mM | 0.0428 mL | 0.2140 mL | 0.4279 mL | 1.0698 mL | |
| 20 mM | 0.0321 mL | 0.1605 mL | 0.3209 mL | 0.8024 mL | |
| 25 mM | 0.0257 mL | 0.1284 mL | 0.2568 mL | 0.6419 mL | |
| 30 mM | 0.0214 mL | 0.1070 mL | 0.2140 mL | 0.5349 mL | |
| 40 mM | 0.0160 mL | 0.0802 mL | 0.1605 mL | 0.4012 mL | |
| 50 mM | 0.0128 mL | 0.0642 mL | 0.1284 mL | 0.3209 mL | |
| 60 mM | 0.0107 mL | 0.0535 mL | 0.1070 mL | 0.2675 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.