2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. 11-Deoxy prostaglandin E1

11-Deoxy prostaglandin E1  (Synonyms: AY-23578; Doproston B; 11-Deoxy-PGE1)

Cat. No.: HY-128043
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11-Deoxy prostaglandin E1 (AY-23578; Doproston B) is an analog of prostaglandin E1 (PGE1) with bronchodilator activity. 11-Deoxy prostaglandin E1 inhibits histamine-induced bronchoconstriction and causes relaxation of tracheal strips in isolated guinea pigs.

For research use only. We do not sell to patients.

11-Deoxy prostaglandin E1 Chemical Structure

11-Deoxy prostaglandin E1 Chemical Structure

CAS No. : 37786-00-8

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11-Deoxy prostaglandin E1 Related Antibodies

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Description

11-Deoxy prostaglandin E1 (AY-23578; Doproston B) is an analog of prostaglandin E1 (PGE1) with bronchodilator activity. 11-Deoxy prostaglandin E1 inhibits histamine-induced bronchoconstriction and causes relaxation of tracheal strips in isolated guinea pigs[1].

In Vitro

11-Deoxy prostaglandin E1 (100 μg/mL) exhibits a relaxing effect on isolated guinea pig tracheal strips contracted by Carbachol (1 μg/kg)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

11-Deoxy prostaglandin E1 Related Antibodies
In Vivo

11-Deoxy prostaglandin E1 (administered as a spray) has no significant bronchodilator effect in guinea pigs and cats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

338.48

Formula

C20H34O4
CAS No.
SMILES

OC(CCCCCC[C@@H]1[C@H](CCC1=O)/C=C/[C@@H](O)CCCCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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11-Deoxy prostaglandin E1 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11-Deoxy prostaglandin E137786-00-8AY-23578 Doproston B 11-Deoxy-PGE1AY23578AY 23578Prostaglandin ReceptorbronchiectasistracheoconstrictionhormonesInhibitorinhibitorinhibit

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11-Deoxy prostaglandin E1
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