2,3-Pentanedione-d5
Based on 1 Customer Validation
2,3-Pentanedione-d5 is the deuterium labeled 2,3-Pentanedione (HY-W012998). 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans.
For research use only. We do not sell to patients.
- Purity: 98.00%
- CAS No.: 352431-46-0
- Formula: C5H3D5O2
- Molecular Weight:105.15
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 352431-46-0
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Appearance Liquid
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Molecular Weight 105.15
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Formula C5H3D5O2
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Color Colorless to light yellow
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SMILES
[2H]C([2H])([2H])C(C(C([2H])([2H])C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : ≥ 50 mg/mL (475.51 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (767 KB)
- English - EN (767 KB)
- Français - FR (767 KB)
- Deutsch - DE (767 KB)
- Norwegian - NO (767 KB)
- Español - ES (767 KB)
- Swedish - SV (767 KB)
- Italian - IT (767 KB)
- Korean - KR (767 KB)
- Portuguese - PT (767 KB)
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Handling Instructions (2659 KB)
References
[1]. Morgan DL, et al. Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans. Toxicol Pathol. 2012;40(3):448-465. [Content Brief]
[2]. Das S, et al., Small molecule diketone flavorants diacetyl and 2,3-pentanedione promote neurotoxicity but inhibit amyloid β aggregation. Toxicol Lett. 2019 Jan;300:67-72. [Content Brief]
[3]. Hubbs AF, et al., Respiratory and olfactory cytotoxicity of inhaled 2,3-pentanedione in Sprague-Dawley rats. Am J Pathol. 2012 Sep;181(3):829-44. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 9.5102 mL | 47.5511 mL | 95.1022 mL | 237.7556 mL |
| 5 mM | 1.9020 mL | 9.5102 mL | 19.0204 mL | 47.5511 mL | |
| 10 mM | 0.9510 mL | 4.7551 mL | 9.5102 mL | 23.7756 mL | |
| 15 mM | 0.6340 mL | 3.1701 mL | 6.3401 mL | 15.8504 mL | |
| 20 mM | 0.4755 mL | 2.3776 mL | 4.7551 mL | 11.8878 mL | |
| 25 mM | 0.3804 mL | 1.9020 mL | 3.8041 mL | 9.5102 mL | |
| 30 mM | 0.3170 mL | 1.5850 mL | 3.1701 mL | 7.9252 mL | |
| 40 mM | 0.2378 mL | 1.1888 mL | 2.3776 mL | 5.9439 mL | |
| 50 mM | 0.1902 mL | 0.9510 mL | 1.9020 mL | 4.7551 mL | |
| 60 mM | 0.1585 mL | 0.7925 mL | 1.5850 mL | 3.9626 mL | |
| 80 mM | 0.1189 mL | 0.5944 mL | 1.1888 mL | 2.9719 mL | |
| 100 mM | 0.0951 mL | 0.4755 mL | 0.9510 mL | 2.3776 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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