2′-Deoxy-4′-thiocytidine
2′-Deoxy-4′-thiocytidine (T-dCyd) is a novel epigenetic agent. 2′-Deoxy-4′-thiocytidine administrations led to a significant p21 increase. 2′-Deoxy-4′-thiocytidine can eradicate of tumor cells in the double-mutant xenografts.
For research use only. We do not sell to patients.
- CAS No.: 134111-30-1
- Formula: C9H13N3O3S
- Molecular Weight:243.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA Methyltransferase Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEp-2 | IC50 |
<0.2 μM
Compound: 7Beta
|
The concentration required to produce a 50% inhibition of clone formation in human epidermoid carcinoma H-Ep-2 cells
The concentration required to produce a 50% inhibition of clone formation in human epidermoid carcinoma H-Ep-2 cells
|
[PMID: 1652015] |
| L1210 | IC50 |
1.2 μM
Compound: 7Beta
|
The concentration required to produce a 50% reduction in the rate of cell proliferation in murine leukemia L1210 cells
The concentration required to produce a 50% reduction in the rate of cell proliferation in murine leukemia L1210 cells
|
[PMID: 1652015] |
Chemical Information
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CAS No. 134111-30-1
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Molecular Weight 243.28
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Formula C9H13N3O3S
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SMILES
O=C(N=C(N)C=C1)N1[C@@H]2S[C@H](CO)[C@@H](O)C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)